1H-Indole-5-carbonyl chloride CAS 161397-68-8
| CAS No. | 161397-68-8 |
| Molecular Formula | C9H6ClNO |
| Molecular Weight | 179.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 179.60 g/mol gives 1H-Indole-5-carbonyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1H-Indole-5-carbonyl chloride (CAS 161397-68-8), a certified reference material (molecular formula C9H6ClNO, MW 179.60 g/mol) for analytical method development and quality control.
1H-Indole-5-carbonyl chloride (C9H6ClNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H6ClNO |
| Molecular Weight | 179.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related H Standards
- 1H-Indole-1-carbonyl chloride (CAS 127485-48-7)
- 1H-Indole-7-carbonyl chloride (CAS 1378812-43-1)
- 1H-Indole-2-carbonyl chloride (CAS 58881-45-1)
- 1H-Indole-3-carbonyl ChlorideDISCONTINUED (CAS 59496-25-2)
- 1H-Indole-6-carbonyl chloride (CAS 215941-02-9)
- Indole-2,4,5,6,7-d5-3-acetamide (CAS 1204700-53-7)
- 1H-INDOLE-5-CARBOXYLIC ACID,6-FLUORO (CAS 908600-73-7)
- Indole-2,4,5,6,7-d5-3-acetic Acid (CAS 76937-78-5)
Recommended Standards
- 8-Chloroquinolin-5-ol hydrobromide (CAS 16026-85-0)
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- 2-(5-chloro-1H-1,2,4-triazol-1-yl)propanoic acid (CAS 1790365-80-8)
- Ethyl 2-(6-(naphthalen-2-ylthio)-9H-purin-9-yl)acetate (CAS 646509-78-6)
- N-(2-Chloro-6-nitrophenyl)ethane-1,2-diamine hydrochloride (CAS 298703-19-2)
- 1-[5-(4-Isopropylphenyl)-4-methyl-1,1-dioxido-isothiazol-3-yl]-1,4-diazepane hydrochloride (CAS 1417567-91-9)
- 5-((2H-Pyrrol-2-ylidene)methyl)-2H-pyrrol-2-one (CAS 66560-68-7)
- N-(2-(2-oxopyrrolidin-1-yl)phenyl)isobutyramide (CAS 1281062-68-7)
- Pravastatin 3-beta-Hydroxy Lactone (CAS 87984-67-6)
- 5-Ethynyl-2,3-dimethylpyridine (CAS 1857155-64-6)
- N-(2,4-Dimethylphenyl)-3-(4-methoxyphenyl)-2-(2H-1,2,3,4-tetrazol-5-yl)propanamide (CAS 483993-05-1)
- beta-Nicotyrine (CAS 487-19-4)
- Semaglutide impurity 60 (CAS CATO-C4X-222660)
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