3-Chloro-4-(4-methylpiperazin-1-yl)benzenamine CAS 16154-72-6
| CAS No. | 16154-72-6 |
| Molecular Formula | C11H16ClN3 |
| Molecular Weight | 225.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Chloro-4-(4-methylpiperazin-1-yl)benzenamine (CAS 16154-72-6) is a high-purity analytical reference standard with the molecular formula C11H16ClN3 and a molecular weight of 225.72 g/mol.
The molecular framework of 3-Chloro-4-(4-methylpiperazin-1-yl)benzenamine (C11H16ClN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-Chloro-4-(4-methylpiperazin-1-yl)benzenamine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H16ClN3 |
| Molecular Weight | 225.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
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- 2-Chloro-4-(4-methylpiperazin-1-yl)aniline (CAS 1124330-00-2)
- 6-Chloro-N-cyclohexyl-N-methyl-4-pyrimidinamine (CAS 1219961-12-2)
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Recommended Standards
- 1-(6-Chloropyridin-2-yl)-N,N-dimethylpyrrolidin-3-amine (CAS 159603-33-5)
- 3-Chloro-2-(4-methylpiperazin-1-yl)aniline (CAS 189761-97-5)
- 1-(Bicyclo[2.2.1]heptan-2-ylmethyl)-4-chloro-1h-pyrazol-3-amine (CAS 1560055-07-3)
- 1-((6-Chloropyridin-3-yl)methyl)-4-methylpiperazine (CAS 612487-31-7)
- 6-(Benzylamino)nicotinonitrile (CAS 15871-91-7)
- (S)-2-(4-fluoro-3,5-dimethylphenyl)pyrrolidine (CAS 1213060-87-7)
- 2,2-Dimethyldihydro-2H-pyran-3(4H)-one (CAS 1194800-59-3)
- 3'-methoxy-[1,1'-biphenyl]-4-carbaldehyde (CAS 209863-09-2)
- Vortioxetine Impurity 70 (CAS CATO-C4X-105670)
- N-methyl-1-(spiro[3.3]Heptan-2-yl)methanamine (CAS 1498137-99-7)
- <I>N</I>-Sulfenylanilide (CAS 1122-83-4)
- 7-(4-Chlorophenyl)-2-ethyl-[1,2,4]triazolo[1,5-a]pyridine-8-carbonitrile (CAS 860611-34-3)
- 2'-Chloro-6'-fluoro-5-hydroxy-4-(1,2,3,4-tetrahydroisoquinolin-1-yl)-1,6-dihydro-[1,1'-biphenyl]-3(2H)-one (CAS 338793-14-9)
- Semaglutide Impurity 145 (CAS CATO-C4X-2226145)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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