1-Cbz-4-cyanopiperidine CAS 161609-84-3
| CAS No. | 161609-84-3 |
| Molecular Formula | C14H16N2O2 |
| Molecular Weight | 244.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1-Cbz-4-cyanopiperidine (CAS 161609-84-3), a certified reference material (molecular formula C14H16N2O2, MW 244.29 g/mol) for analytical method development and quality control.
1-Cbz-4-cyanopiperidine (C14H16N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H16N2O2 |
| Molecular Weight | 244.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Nitrogen Atoms | 2 |
Related Cbz Standards
- Benzyl 2-cyanopiperidine-1-carboxylate (CAS 1017788-63-4)
- 1-Cbz-3-Cyanopiperidine (CAS 885069-22-7)
- 1-Boc-2-cyanopiperidine (CAS 153749-89-4)
- 1-Boc-3-Cyanopiperidine (CAS 91419-53-3)
- 4-Cyanopiperidine-1-sulfonyl chloride (CAS 1392803-35-8)
- Ethyl 4-cyanopiperidine-4-carboxylate (CAS 123755-34-0)
- Ethyl 1-cyanopiperidine-4-carboxylate (CAS 1564465-45-7)
- Ethyl 4-cyanopiperidine-1-carboxylate (CAS 182808-28-2)
Recommended Standards
- tert-Butyl (1-(methoxy(methyl)carbamoyl)cyclopropyl)carbamate (CAS 161521-10-4)
- tert-butyl 3-(1-amino-2-methoxy-2-oxoethyl)azetidine-1-carboxylate (CAS 1620451-38-8)
- Methyl 1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate (CAS 16108-10-4)
- 4-(1,3-Benzothiazol-2-yl)-3-fluoroaniline (CAS 162374-62-1)
- 3-(2-(Piperidin-1-yl)ethoxy)benzaldehyde (CAS 81068-27-1)
- 4-(Hydroxymethyl)-2-iodo-6-methoxyphenol (CAS 37987-21-6)
- N-(3-Hydroxy-4-(hydroxymethyl)cyclopentyl)-4-methyl-2-(1H-pyrrol-1-yl)thiazole-5-carboxamide (CAS 1421514-91-1)
- tert-Butyl(1,1,1-trifluoro-4-hydroxybutan-2-yl)carbamate (CAS 1402429-03-1)
- (E)-1,1,1-Trifluoro-4-phenylbut-3-en-2-ol (CAS 89524-18-5)
- Ethyl 4-hydroxyazepane-1-carboxylate (CAS 109386-74-5)
- 5-Cyano-3-cyclopropoxy-N,N-dimethylpicolinamide (CAS 1243405-66-4)
- Methyl 3-amino-6-fluoropyrazine-2-carboxylate (CAS 356783-41-0)
- (11bS)-2,6-Bis(3,5-dimethylphenyl)-4-hydroxydinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepine 4-Oxide (CAS 1170736-59-0)
- Exenatide (CAS 141758-74-9)
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