EPZ015866, 98%, a potent and selective inhibitor of protein methyltransferase 5 (PRMT5) CAS 1616391-87-7
| CAS No. | 1616391-87-7 |
| Molecular Formula | C22H28N4O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), EPZ015866, 98%, a potent and selective inhibitor of protein methyltransferase 5 (PRMT5) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
EPZ015866, 98%, a potent and selective inhibitor of protein methyltransferase 5 (PRMT5) (CAS 1616391-87-7), molecular formula C22H28N4O2HCl and molecular weight 416.95 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, EPZ015866, 98%, a potent and selective inhibitor of protein methyltransferase 5 (PRMT5) (C22H28N4O2HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 416.95 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H28N4O2 2*HCl |
| Molecular Weight | 416.95 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Recommended Standards
- 5-methyl-4-oxo-3H,4H-pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid (CAS 310435-15-5)
- Ethyl 3-methyl-5-phenyl-1H-pyrazole-4-carboxylatehydrochloride (CAS 1452577-05-7)
- 1-(2-chlorophenyl)-3-methyl-1H-pyrazole (CAS 1613303-64-2)
- 6-Bromo-8-fluoroquinolin-3-amine (CAS 2090478-87-6)
- 2-((2-Hydroxyethyl)thio)-1-(2-methoxyphenyl)ethan-1-one (CAS 1157307-81-7)
- 5-(benzyloxy)-3H-spiro[1-benzofuran-2,1’-cyclopropane]-3-one (CAS 72492-09-2)
- 2-Cyclopropyl-5-methylpyridin-3-amine (CAS 1544882-25-8)
- Trifarotene Impurity 3 (CAS CATO-C4X-31323)
- Ethyl Salicylate (CAS 118-61-6)
- Tau Peptide (277-291) trifluoroacetate salt (CAS 330456-40-1)
Why CATO?
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