6,7-Dichloro-4-(4-chlorophenyl)-2-(4-(trifluoromethoxy)phenyl)phthalazin-1(2H)-one CAS 161716-24-1
| CAS No. | 161716-24-1 |
| Molecular Formula | C21H10Cl3F3N2O2 |
| Molecular Weight | 485.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6,7-Dichloro-4-(4-chlorophenyl)-2-(4-(trifluoromethoxy)phenyl)phthalazin-1(2H)-one.
6,7-Dichloro-4-(4-chlorophenyl)-2-(4-(trifluoromethoxy)phenyl)phthalazin-1(2H)-one (CAS 161716-24-1) is a high-purity analytical reference standard with the molecular formula C21H10Cl3F3N2O2 and a molecular weight of 485.67 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 6,7-Dichloro-4-(4-chlorophenyl)-2-(4-(trifluoromethoxy)phenyl)phthalazin-1(2H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 485.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H10Cl3F3N2O2 |
| Molecular Weight | 485.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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