Olmesartan Impurity 76 CAS 161952-66-5
| CAS No. | 161952-66-5 |
| Molecular Formula | C14H11ClN4 |
| Molecular Weight | 270.72 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Olmesartan Impurity 76 (C14H11ClN4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Olmesartan Impurity 76 (CAS 161952-66-5) is a certified pharmaceutical impurity reference standard with the molecular formula C14H11ClN4 and a molecular weight of 270.72 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Olmesartan Impurity 76 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H11ClN4 |
| Molecular Weight | 270.72 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Olmesartan Standards
- Olmesartan impurity 88 (CAS CATO-C4X-109788)
- Olmesartan Impurity 57 (CAS CATO-C4X-109757)
- Olmesartan Impurity 29 (CAS 76-83-5)
- Olmesartan Impurity 32 (CAS 1092980-85-2)
- Olmesartan Impurity 36 (CAS 1092980-84-1)
- Olmesartan Impurity 37 (CAS 172875-53-5)
- Olmesartan impurity 98 (CAS CATO-C4X-109798)
- Olmesartan Impurity 17 (CAS 144689-94-1)
Recommended Standards
- Tribromofluoromethane (CAS 353-54-8)
- (E)-Nitenpyram (CAS 150824-47-8)
- N4-(4-Chlorophenyl)quinazoline-4,6-diamine (CAS 749884-54-6)
- Nitenpyram (CAS 120738-89-8)
- Ipconazole Impurity 2 (CAS 115937-89-8)
- Oxacillin Impurity 48 (CAS CATO-C4X-232148)
- Folic Acid EP Impurity G (CAS 2734707-85-6)
- 5-Methoxyisoindoline hydrobromide (CAS 1056165-25-3)
- 6-Bromo-4-chloro-1-methylquinazolin-2(1H)-one (CAS 2660143-57-5)
- (S)-2-Chloropentanedioic acid (CAS 1369533-83-4)
- Dibenzyl Phthalate-d4 (CAS 1015854-62-2)
- DCPIB (CAS 82749-70-0)
- N-(5-Bromo-2-(trifluoromethoxy)phenyl)acetamide (CAS 392726-69-1)
- Serpent Peptide (CAS 823202-99-9)
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