4-(4-(4-Fluorophenyl)-5-oxo-2,5-dihydrofuran-3-yl)benzenesulfonamide CAS 162012-33-1

Purity 97%+In StockPharmaceutical Standards
CAS No.162012-33-1
Molecular FormulaC16H12FNO4S
Molecular Weight333.33 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(4-(4-Fluorophenyl)-5-oxo-2,5-dihydrofuran-3-yl)benzenesulfonamide CAS 162012-33-1 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(4-(4-Fluorophenyl)-5-oxo-2,5-dihydrofuran-3-yl)benzenesulfonamide.

4-(4-(4-Fluorophenyl)-5-oxo-2,5-dihydrofuran-3-yl)benzenesulfonamide (CAS 162012-33-1) is a high-purity analytical reference standard with the molecular formula C16H12FNO4S and a molecular weight of 333.33 g/mol.

Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 4-(4-(4-Fluorophenyl)-5-oxo-2,5-dihydrofuran-3-yl)benzenesulfonamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 333.33 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC16H12FNO4S
Molecular Weight333.33 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2003
Halogen ContentF-containing
Nitrogen Atoms1
Sulfur Atoms1

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