3-(Trimethylsilyl)propiolate ethyl ester CAS 16205-84-8
| CAS No. | 16205-84-8 |
| Molecular Formula | C8H14O2Si |
| Molecular Weight | 170.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(Trimethylsilyl)propiolate ethyl ester is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(Trimethylsilyl)propiolate ethyl ester (CAS 16205-84-8), molecular formula C8H14O2Si and molecular weight 170.28 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, 3-(Trimethylsilyl)propiolate ethyl ester is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 170.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(Trimethylsilyl)propiolate ethyl ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H14O2Si |
| Molecular Weight | 170.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1961 |
Related Trimethylsilyl Standards
- 3-((Trimethylsilyl)ethynyl)oxetan-3-ol (CAS 1242160-02-6)
- Methyl 4-(trimethylsilyl)but-3-ynoate (CAS 319919-26-1)
- 6-(Trimethylsilyl)hex-5-yn-1-ol (CAS 103437-52-1)
- 3-Methyl-1-trimethylsilyl-1-pentyn-3-ol(+/-) (CAS 17889-43-9)
- 4-(Trimethylsilyl)cyclohexan-1-one (CAS 7452-95-1)
- Bis(trimethylsilyl)acetylene (CAS 14630-40-1)
- 6-(Trimethylsilyl)hex-5-yn-1-amine (CAS 1365478-24-5)
- 3-Methyl-2-[(trimethylsilyl)oxy]but-3-enenitrile (CAS 60550-34-7)
Recommended Standards
- 2-Isopropyl-4-(methylaminomethyl)thiazole (CAS 154212-60-9)
- N,N-Diethyl-4-methyl-1,3-thiazol-2-amine (CAS 164397-12-0)
- 2-Methyl-1-(2-methylthiazol-4-yl)propan-2-amine (CAS 1521693-16-2)
- 4-(tert-butyl)thiazole-2-methanamine (CAS 184839-20-1)
- Etoricoxib Impurity 31 (CAS 93629-02-8)
- 11-Oxododecanoic acid (CAS 2388-78-5)
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- Methyl 1-((3-amino-1H-pyrazol-1-yl)methyl)-1H-pyrazole-4-carboxylate (CAS 1006495-06-2)
- 4-Methoxy-N-(4-methoxybenzyl)benzenesulfonamide (CAS 122134-66-1)
- 4-(Di(1H-indol-3-yl)methyl)aniline (CAS 6340-90-5)
- tert-Butyl 1',3'-dioxo-5',7'-dihydro-1'H,3'H-spiro[azetidine-3,6'-indeno[5,6-c]furan]-1-carboxylate (CAS 2830606-89-6)
- 5-Bromo-4,6-dihydroxynicotinic acid (CAS 1216835-16-3)
- 4-(2-imino-3-methyl-5-oxoimidazolidin-1-yl)butanoic acid (CAS 213181-98-7)
- Semaglutide Impurity 131 (CAS 2618647-80-4)
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