2-Methyl-2-phenylacetophenone CAS 16216-13-0

Purity 97%+In StockPharmaceutical Standards
CAS No.16216-13-0
Molecular FormulaC15H14O
Molecular Weight210.27 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Methyl-2-phenylacetophenone CAS 16216-13-0 chemical structure

Description

2-Methyl-2-phenylacetophenone (CAS 16216-13-0), molecular formula C15H14O and molecular weight 210.27 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-Methyl-2-phenylacetophenone (C15H14O) is characterized by a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC15H14O
Molecular Weight210.27 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1961

Recommended Standards

Why CATO?