THieno[3,2-d]pyrimidine, 2,4-dimethoxy- CAS 16229-02-0
| CAS No. | 16229-02-0 |
| Molecular Formula | C8H8N2O2S |
| Molecular Weight | 196.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
THieno[3,2-d]pyrimidine, 2,4-dimethoxy- (CAS 16229-02-0) is a high-purity analytical reference standard with the molecular formula C8H8N2O2S and a molecular weight of 196.23 g/mol.
THieno[3,2-d]pyrimidine, 2,4-dimethoxy- (C8H8N2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), THieno[3,2-d]pyrimidine, 2,4-dimethoxy- meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8N2O2S |
| Molecular Weight | 196.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related THieno Standards
- Thieno[2,3-b]thiophene-2,5-dicarbaldehyde (CAS 41784-82-1)
- 2-(Thieno[3,2-d]pyrimidin-4-ylamino)ethan-1-ol (CAS 16234-53-0)
- 2-(Thieno[2,3-d]pyrimidin-4-ylamino)ethanol (CAS 18734-91-3)
- Methyl thieno[3,2-d]pyrimidine-7-carboxylate (CAS 1356017-03-2)
- Methyl thieno[2,3-d]pyrimidine-4-carboxylate (CAS 175293-84-2)
- Methyl thieno[2,3-b]pyrazine-6-carboxylate (CAS 1824388-08-0)
- Thieno[3,4-b]thiophen-2-yl acetate (CAS 1823323-50-7)
- Methyl thieno[2,3-b]thiophene-2-carboxylate (CAS 20969-37-3)
Recommended Standards
- 6-Methylimidazo[2,1-b]thiazole-5-carbohydrazide (CAS 161563-79-7)
- 5-(Ethylsulfonyl)picolinonitrile (CAS 1649454-78-3)
- 2-Mercapto-6,7-dihydro-5H-cyclopenta[d]pyrimidine-5-carboxylic acid (CAS 1550998-57-6)
- 4-methyl-5-(4-methyloxazol-5-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 170959-40-7)
- Quinoline-4-carbonyl chloride (CAS 50821-72-2)
- 2-(4-Fluorophenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine (CAS 1250444-39-3)
- 3-Chloro-4-(difluoromethyl)-5-methylpyridine (CAS 1805315-16-5)
- HA-100 (dihydrochloride) (CAS 210297-47-5)
- Posaconazole Impurity 111 (CAS 112559-81-6)
- Isopropyl 3-iodo-2-methyl-4-oxo-1,4-dihydroquinoline-6-carboxylate (CAS 1330752-06-1)
- 1-Chloro-3-(4-methylphenyl)propan-2-one (CAS 24253-14-3)
- Fosaprepitant Impurity 4 Dimeglumine (CAS 1523569-87-0)
- N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-2-((3-cyano-6-cyclopropyl-4-(trifluoromethyl)pyridin-2-yl)thio)acetamide (CAS 625377-50-6)
- Semaglutide impurity 199 (CAS CATO-C4X-2226199)
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