Abrocitinib Impurity 16 DiHBr CAS 1622903-42-7
| CAS No. | 1622903-42-7 |
| Molecular Formula | C18H21N5O2S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Abrocitinib Impurity 16 DiHBr is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Abrocitinib Impurity 16 DiHBr (CAS 1622903-42-7), a certified reference material (molecular formula C18H21N5O2SHBr, MW 452.37 g/mol) for analytical method development and quality control.
The molecular framework of Abrocitinib Impurity 16 DiHBr (C18H21N5O2SHBr) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Abrocitinib Impurity 16 DiHBr under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H21N5O2S 2*HBr |
| Molecular Weight | 452.37 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Abrocitinib Standards
- Abrocitinib Impurity 56 (CAS 1208319-36-1)
- Abrocitinib (CAS 1622902-68-4)
- Abrocitinib Related Compound 3 (CAS 1622980-99-7)
- Abrocitinib Impurity 48 HBr (CAS 1622981-00-3(free base))
- Abrocitinib Impurity 24 (CAS 1622981-01-4)
- Abrocitinib Impurity 23 (CAS 2204275-76-1)
- Abrocitinib Impurity 29 (CAS 2204276-97-9)
- Abrocitinib Impurity 3 (CAS 2204280-33-9)
Recommended Standards
- 3-Bromo-N1,N1-dimethylbenzene-1,4-diamine (CAS 107100-00-5)
- Ethyl 2-(3-bromopropanamido)-5-ethylthiophene-3-carboxylate (CAS 331666-25-2)
- 2-Chloro-N-(tetrahydro-1,1-dioxido-3-thienyl)acetamide (CAS 5612-41-9)
- 2-(Difluoromethyl)-3-fluoro-6-methylpyridine-4-carboxaldehyde (CAS 1805611-05-5)
- 3-Methyl-7,8-dihydroquinolin-6(5H)-one (CAS 944895-67-4)
- 4'-Methoxy[1,1'-biphenyl]-4-carbonitrile (CAS 893737-67-2)
- Sodium undecanoate (CAS 17265-30-4)
- 4’-(Bromomethyl)acetophenone (CAS 51229-51-7)
- [[2′,6′-Bis(1-methylethoxy)[1,1′-biphenyl]-2-yl]dicyclohexylphosphine-κP]chlorogold (CAS 1261452-57-6)
- Fragment-[7-31]-Liraglutide (CAS CATO-C4X-199239)
Why CATO?
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