4-chloro-6,7-diethoxy-quinazoline CAS 162363-46-4
| CAS No. | 162363-46-4 |
| Molecular Formula | C12H23ClN2O2 |
| Molecular Weight | 262.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-chloro-6,7-diethoxy-quinazoline is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-chloro-6,7-diethoxy-quinazoline (CAS 162363-46-4), molecular formula C12H23ClN2O2 and molecular weight 262.78 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-chloro-6,7-diethoxy-quinazoline (C12H23ClN2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-chloro-6,7-diethoxy-quinazoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H23ClN2O2 |
| Molecular Weight | 262.78 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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- 1-(chloromethyl)-4-isocyanato-benzene 1-(chloromethyl)-4-isocyanatobenzene 29173-65-7 A819795 (CAS 29173-65-7)
- N-(2-Methyl-3-(5-methylbenzo[d]oxazol-2-yl)phenyl)-3-nitrobenzamide (CAS 331668-01-0)
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- Semaglutide impurity 56 (CAS CATO-C4X-222656)
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