(5-chlorothiophen-2-yl)boronic acid CAS 162607-18-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (5-chlorothiophen-2-yl)boronic acid.

CATO supplies (5-chlorothiophen-2-yl)boronic acid (CAS 162607-18-3), a certified reference material (molecular formula C4H8BClO2S, MW 166.43 g/mol) for analytical method development and quality control.

The molecular framework of (5-chlorothiophen-2-yl)boronic acid (C4H8BClO2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (5-chlorothiophen-2-yl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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