5,7-Dichlorobenzo[d]isoxazol-3-amine CAS 16263-60-8
| CAS No. | 16263-60-8 |
| Molecular Formula | C7H4Cl2N2O |
| Molecular Weight | 203.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5,7-Dichlorobenzo[d]isoxazol-3-amine.
CATO supplies 5,7-Dichlorobenzo[d]isoxazol-3-amine (CAS 16263-60-8), a certified reference material (molecular formula C7H4Cl2N2O, MW 203.03 g/mol) for analytical method development and quality control.
The molecular framework of 5,7-Dichlorobenzo[d]isoxazol-3-amine (C7H4Cl2N2O) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5,7-Dichlorobenzo[d]isoxazol-3-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4Cl2N2O |
| Molecular Weight | 203.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichlorobenzo Standards
- 5,6-Dichlorobenzo[d]oxazol-2-amine (CAS 64037-12-3)
- 1,3-Dichlorobenzo[c]thiophene (CAS 136132-54-2)
- 3,6-Dichlorobenzo[b]thiophene (CAS 21211-21-2)
- 4,7-Dichlorobenzo[b]thiophene (CAS 318463-07-9)
- 6,7-Dichlorobenzo[b]thiophene (CAS 439083-10-0)
- 5,6-Dichlorobenzo[d]oxazol-2(3H)-one (CAS 5285-41-6)
- 5,7-Dichlorobenzo[c][1,2,5]oxadiazol-4-amine (CAS 330982-41-7)
- 5,7-Dichlorobenzo[d]isoxazol-3(2H)-one (CAS 66571-27-5)
Recommended Standards
- 3-(5-Bromofuran-2-yl)prop-2-en-1-ol (CAS 1564033-40-4)
- 2-Bromo-1-(5-methylfuran-2-yl)ethanone (CAS 1634-53-3)
- 1-(5-Bromofuran-2-yl)prop-2-en-1-ol (CAS 1488849-07-5)
- 5-Bromo-2-(hydroxymethyl)phenol (CAS 170434-11-4)
- 1-methylcyclopent-3-en-1-amine hydrochloride (CAS 1909320-31-5)
- tert-Butyl 2-phenylpyrrolidine-1-carboxylate (CAS 154874-88-1)
- 6-Methyl-2,3,5,6,7,8-hexahydrocinnolin-3-one (CAS 39716-44-4)
- 3-Methoxy-2-[2-(4-morpholinyl)ethoxy]benzaldehyde hydrochloride (CAS 1609409-33-7)
- 6-(2-Hydroxyphenyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS 55982-10-0)
- 5-(Hydroxymethyl)furan-2-carbohydrazide (CAS 859303-94-9)
- 4-(2,3-Dimethoxyphenyl)-4-oxobutyric acid (CAS 898792-27-3)
- tert-Butyl 5-hydroxy-2-methylpiperidine-1-carboxylate (CAS 362704-65-2)
- Ergosterol peroxide (CAS 2061-64-5)
- Insulin degludec (CAS 844439-96-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com