Rel-2-((((1R,4r)-4-((R)-1-amino-2-(7-fluoro-2-oxoquinoxalin-1(2H)-yl)ethyl)cyclohexyl)amino)methyl)-5H-pyrimido[4,5-b][1,4]oxazin-6(7H)-one CAS 1626428-30-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1626428-30-5
Molecular FormulaC23H26FN7O3
Molecular Weight467.50 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Rel-2-((((1R,4r)-4-((R)-1-amino-2-(7-fluoro-2-oxoquinoxalin-1(2H)-yl)ethyl)cyclohexyl)amino)methyl)-5H-pyrimido[4,5-b][1,4]oxazin-6(7H)-one CAS 1626428-30-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Rel-2-((((1R,4r)-4-((R)-1-amino-2-(7-fluoro-2-oxoquinoxalin-1(2H)-yl)ethyl)cyclohexyl)amino)methyl)-5H-pyrimido[4,5-b][1,4]oxazin-6(7H)-one.

CATO supplies Rel-2-((((1R,4r)-4-((R)-1-amino-2-(7-fluoro-2-oxoquinoxalin-1(2H)-yl)ethyl)cyclohexyl)amino)methyl)-5H-pyrimido[4,5-b][1,4]oxazin-6(7H)-one (CAS 1626428-30-5), a certified reference material (molecular formula C23H26FN7O3, MW 467.50 g/mol) for analytical method development and quality control.

The molecular framework of Rel-2-((((1R,4r)-4-((R)-1-amino-2-(7-fluoro-2-oxoquinoxalin-1(2H)-yl)ethyl)cyclohexyl)amino)methyl)-5H-pyrimido[4,5-b][1,4]oxazin-6(7H)-one (C23H26FN7O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Rel-2-((((1R,4r)-4-((R)-1-amino-2-(7-fluoro-2-oxoquinoxalin-1(2H)-yl)ethyl)cyclohexyl)amino)methyl)-5H-pyrimido[4,5-b][1,4]oxazin-6(7H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC23H26FN7O3
Molecular Weight467.50 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1993
Halogen ContentF-containing
Nitrogen Atoms7

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