4-Chlorothieno[3,2-d]pyrimidine CAS 16269-66-2
| CAS No. | 16269-66-2 |
| Molecular Formula | C6H3ClN2S |
| Molecular Weight | 170.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chlorothieno[3,2-d]pyrimidine.
CATO supplies 4-Chlorothieno[3,2-d]pyrimidine (CAS 16269-66-2), a certified reference material (molecular formula C6H3ClN2S, MW 170.62 g/mol) for analytical method development and quality control.
The molecular framework of 4-Chlorothieno[3,2-d]pyrimidine (C6H3ClN2S) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H3ClN2S |
| Molecular Weight | 170.62 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorothieno Standards
- 2-Chlorothieno[3,2-d]pyrimidine (CAS 1119280-68-0)
- 4-Chlorothieno[3,4-d]pyrimidine (CAS 1196155-02-8)
- 4-Chlorothieno[2,3-d]pyrimidine (CAS 14080-59-2)
- 4-Chlorothieno[2,3-d]pyridazine (CAS 697-68-7)
- 7-Chlorothieno[2,3-b]pyrazine (CAS 59944-74-0)
- 7-Chlorothieno[2,3-d]pyridazine (CAS 697-71-2)
- 7-Chlorothieno[3,2-d]pyrimidine (CAS 31492-65-6)
- 6-Chlorothieno[3,2-c]pyridine (CAS 1781989-24-9)
Recommended Standards
- 7-Chlorothiazolo[4,5-b]pyridine (CAS 1556129-57-7)
- 5-Chloro-4-mercaptonicotinonitrile (CAS 1706445-79-5)
- 5-Chloro-2-thioxo-1,2-dihydropyridine-3-carbonitrile (CAS 1501132-54-2)
- 2-Chloro-3-isothiocyanatopyridine (CAS 50470-12-7)
- 5-[(2,4-dichlorophenyl)methyl]-1,3-thiazol-2-amine (CAS 301223-42-7)
- 3-((Methylsulfinyl)methyl)-4-(octyloxy)aniline (CAS 5819-61-4)
- 1-Acetyl-2,6-dimethoxynaphthalene (CAS 86539-77-7)
- (1-Methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)methanamine (CAS 1370514-97-8)
- 1-Amino-3-(5-chloro-2-methoxyphenyl)propan-2-ol (CAS 1225956-59-1)
- (S)-8-(2-Hydroxy-3-methylbut-3-en-1-yl)-7-methoxy-2H-chromen-2-one (CAS 1221-43-8)
- 2-(Dimethylamino)-N-(2-(piperidin-4-yl)ethyl)acetamide (CAS 1185533-68-9)
- Methyl nitrite (CAS 624-91-9)
- Dipentadecyl [1,1'-biphenyl]-4,4'-dicarboxylate (CAS 80911-53-1)
- ([D?]Val?·1?)-C-Peptide (human) (CAS 1802078-41-6)
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