tert-Butyl (trans-4-fluoro-4-(hydroxymethyl)cyclohexyl)carbamate CAS 1627209-58-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1627209-58-8
Molecular FormulaC12H22FNO3
Molecular Weight247.31 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-Butyl (trans-4-fluoro-4-(hydroxymethyl)cyclohexyl)carbamate CAS 1627209-58-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including tert-Butyl (trans-4-fluoro-4-(hydroxymethyl)cyclohexyl)carbamate.

tert-Butyl (trans-4-fluoro-4-(hydroxymethyl)cyclohexyl)carbamate (CAS 1627209-58-8) is a high-purity analytical reference standard with the molecular formula C12H22FNO3 and a molecular weight of 247.31 g/mol.

The molecular framework of tert-Butyl (trans-4-fluoro-4-(hydroxymethyl)cyclohexyl)carbamate (C12H22FNO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), tert-Butyl (trans-4-fluoro-4-(hydroxymethyl)cyclohexyl)carbamate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H22FNO3
Molecular Weight247.31 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1993
Halogen ContentF-containing
Nitrogen Atoms1

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