5-Bromo-1,3-difluoro-2-(methoxymethyl)benzene CAS 162744-61-8
| CAS No. | 162744-61-8 |
| Molecular Formula | C8H7BrF2O |
| Molecular Weight | 237.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-Bromo-1,3-difluoro-2-(methoxymethyl)benzene (C8H7BrF2O) is characterized by a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 5-Bromo-1,3-difluoro-2-(methoxymethyl)benzene (CAS 162744-61-8), a certified reference material (molecular formula C8H7BrF2O, MW 237.04 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Bromo-1,3-difluoro-2-(methoxymethyl)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7BrF2O |
| Molecular Weight | 237.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 1-bromo-4-(difluoromethoxy)-2-methylbenzene (CAS 1021172-76-8)
- 6-Bromo-2,3-difluorophenetole (CAS 1122410-43-8)
- 5-Bromo-2-ethoxy-1,3-difluorobenzene (CAS 115467-04-4)
- 1-Bromo-2-(difluoromethyl)-4-methoxybenzene (CAS 1214329-81-3)
- 3-Bromo-4-(difluoromethyl)anisole (CAS 1214379-79-9)
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- 1-Bromo-4-(difluoro(methoxy)methyl)benzene (CAS 1236031-38-1)
- 1-Bromo-2-ethoxy-3,5-difluorobenzene (CAS 1242418-44-5)
Recommended Standards
- 1-Bromo-2,3-difluoro-4-(methoxymethyl)benzene (CAS 162744-57-2)
- (4-iodo-1-methyl-1H-pyrazol-3-yl)methanamine (CAS 1707568-56-6)
- 1-Bromo-4-ethoxy-2,3-difluorobenzene (CAS 156573-09-0)
- 2-(4-Bromophenyl)-2,2-difluoroethan-1-ol (CAS 1779939-06-8)
- (4-(Morpholinomethyl)phenyl)(m-tolyl)methanone (CAS 898769-64-7)
- 1-(1H-Pyrrol-2-yl)ethan-1-ol (CAS 56423-57-5)
- 4-Benzyl-5-(benzylimino)-4,5-dihydro-1,3,4-thiadiazole-2-thiol (CAS 565195-78-0)
- N-(pentan-3-yl)tetrahydro-2H-thiopyran-4-amine (CAS 1153349-51-9)
- N-{4-[(4-benzylpiperazin-1-yl)sulfonyl]phenyl}acetamide (CAS 294885-65-7)
- Hematoxylin Hydrate (CAS 517-28-2)
- 1-Bromo-4-(4-fluorophenyl)isoquinolin-3-amine (CAS 127999-80-8)
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- 2-(Piperidin-4-ylmethyl)aniline (CAS 1187228-45-0)
- [3-31]-Semaglutide D (Sodium salt) (CAS CATO-C4X-2226119)
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