5-Chloro-3-(2,2,2-trifluoroethyl)-3H-imidazo[4,5-b]pyridin-2-amine CAS 1627952-82-2
| CAS No. | 1627952-82-2 |
| Molecular Formula | C8H6ClF3N4 |
| Molecular Weight | 250.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Chloro-3-(2,2,2-trifluoroethyl)-3H-imidazo[4,5-b]pyridin-2-amine (CAS 1627952-82-2), molecular formula C8H6ClF3N4 and molecular weight 250.61 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C8H6ClF3N4, 5-Chloro-3-(2,2,2-trifluoroethyl)-3H-imidazo[4,5-b]pyridin-2-amine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 250.61 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Chloro-3-(2,2,2-trifluoroethyl)-3H-imidazo[4,5-b]pyridin-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClF3N4 |
| Molecular Weight | 250.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 4-Chloro-1-methyl-3-(2,2,2-trifluoroethyl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 1245643-17-7)
- 6-Chloro-7,8-dimethyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1394040-15-3)
- 4-Chloro-1-ethyl-6-(trifluoromethyl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 1443286-60-9)
- 6-Chloro-1-(1,1,1-trifluoropropan-2-yl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 1443286-70-1)
- 6-Chloro-3-(3,3,3-trifluoropropyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1481327-50-7)
- 6-Chloro-9-ethyl-8-(trifluoromethyl)-9H-purine (CAS 1610706-80-3)
- 2-Chloro-9-ethyl-6-(trifluoromethyl)-9H-purine (CAS 1644-24-2)
- 6-Chloro-7-ethyl-2-(trifluoromethyl)-7H-purine (CAS 1710292-63-9)
Recommended Standards
- 6-Chloro-1-(2,2,2-trifluoroethyl)-1H-pyrazolo[4,3-c]pyridin-3-amine (CAS 2416967-98-9)
- N,N-Diisopropyl-S-(trichloromethyl)thiohydroxylamine (CAS 13029-21-5)
- 6-Formyl-4-nitropyridine-2-sulfonyl chloride (CAS 1393550-56-5)
- Dibenzo[d,f][1,3,2]dioxaphosphepin, 6-chloro- (CAS 16611-68-0)
- 5-butylimidazolidine-2,4-dione (CAS 102716-78-9)
- Ethyl 5-amino-4-iodo-1-(p-tolyl)-1H-pyrazole-3-carboxylate (CAS 1427010-79-4)
- 2,5-Dimethylpyrazolo[1,5-a]pyrimidine-7-carboxylic acid (CAS 1011355-87-5)
- 1-(4-(2-Aminoethyl)-2-methylpiperazin-1-yl)ethanone (CAS 1353982-71-4)
- tert-Butyl 4-{2-oxo-1H,2H,3H-imidazo-[4,5-b]pyridin-1-yl}piperidine-1-carboxylate (CAS 781649-87-4)
- 3-(Benzyloxy)-5-bromobenzoic acid (CAS 1242336-70-4)
- 1-(1-p-Tolyl-ethyl)-piperazine dihydrochloride (CAS 1185298-93-4)
- Methyl 5-bromo-2-methyl-1H-pyrrole-3-carboxylate (CAS 1561780-81-1)
- 5-Chloro-2,4-dimethoxybenzoic acid (CAS 23053-81-8)
- Acetyl tetrapeptide-9(Dermican LS 9837) (CAS 928006-50-2)
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