(4-(Difluoromethoxy)-2,5-difluorophenyl)boronic acid CAS 1628442-69-2
| CAS No. | 1628442-69-2 |
| Molecular Formula | C7H5BF4O3 |
| Molecular Weight | 223.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (4-(Difluoromethoxy)-2,5-difluorophenyl)boronic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(4-(Difluoromethoxy)-2,5-difluorophenyl)boronic acid (CAS 1628442-69-2), molecular formula C7H5BF4O3 and molecular weight 223.92 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (4-(Difluoromethoxy)-2,5-difluorophenyl)boronic acid (C7H5BF4O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (4-(Difluoromethoxy)-2,5-difluorophenyl)boronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5BF4O3 |
| Molecular Weight | 223.92 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
Related Difluoromethoxy Standards
- (4-(Difluoromethoxy)-3,5-difluorophenyl)boronic acid (CAS 915401-97-7)
- 2-(Difluoromethoxy)-4,6-difluorobenzoic acid (CAS 1214326-16-5)
- 2-(Difluoromethoxy)-3,5-difluorobenzoic acid (CAS 1214332-98-5)
- 2-(Difluoromethoxy)-4,5-difluorobenzoic acid (CAS 1214364-06-3)
- 4-(difluoromethoxy)-2,6-difluorobenzoic acid (CAS 1214367-17-5)
- 3-(Difluoromethoxy)-2,6-difluorobenzoic acid (CAS 1214379-50-6)
- 4-(Difluoromethoxy)benzenesulfonic acid (CAS 142739-04-6)
- 3-(Difluoromethoxy)-5-methoxythiophene-2-carboxylic acid (CAS 1707609-66-2)
Recommended Standards
- 2-Fluoro-6-trifluoromethoxy-phenyl boronic acid (CAS 1261214-72-5)
- 3-Fluoro-4-(trifluoromethoxy)phenylboronic Acid (CAS 187804-79-1)
- 2,2-Dibromomalononitrile (CAS 1885-23-0)
- (2,3,5,6-Tetrafluoro-4-methoxyphenyl)boronic acid (CAS 871126-20-4)
- [4-(1,3-Benzothiazol-2-ylsulfanyl)-3-nitrophenyl]methyl 3-(trifluoromethyl)benzoate (CAS 320424-22-4)
- N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-N-methyl-D-allothreonine (CAS 2360825-89-2)
- 3-Iodo-4-(2-methoxyacetamido)benzoic acid (CAS 1131614-49-7)
- 1,4-Anhydro-3,5-bis-O-(tert-butyldimethylsilyl)2-deoxy-D-erythro-pent-1-enitol (CAS 173327-56-5)
- (2S)-2-Amino-1-phenylpropane-1,3-diol (CAS 920277-22-1)
- 3-Methoxy-N-((1-methyl-3-nitro-1H-pyrazol-5-yl)methyl)propan-1-amine hydrochloride (CAS 1856071-58-3)
- Methyl 3-(2-chloroacetamido)-5-fluoro-1H-indole-2-carboxylate (CAS 843631-16-3)
- H-Gly-Gly-Gly-Gly-Gly-OH (CAS 7093-67-6)
- Methyl 2-bromo-5-((tert-butoxycarbonyl)amino)-4-methylbenzoate (CAS 2403843-09-2)
- Immunstimulating Peptide, human (CAS 94773-24-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com