5-Bromo-3-(trifluoromethyl)-1,2-thiazole-4-carbonitrile CAS 1628451-85-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1628451-85-3
Molecular FormulaC5BrF3N2S
Molecular Weight257.03 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Bromo-3-(trifluoromethyl)-1,2-thiazole-4-carbonitrile CAS 1628451-85-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 257.03 g/mol gives 5-Bromo-3-(trifluoromethyl)-1,2-thiazole-4-carbonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 5-Bromo-3-(trifluoromethyl)-1,2-thiazole-4-carbonitrile (CAS 1628451-85-3), a certified reference material (molecular formula C5BrF3N2S, MW 257.03 g/mol) for analytical method development and quality control.

Owing to a nitrile group, sulfur-containing functionality, fluorine/bromine substitution, 5-Bromo-3-(trifluoromethyl)-1,2-thiazole-4-carbonitrile is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 257.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Bromo-3-(trifluoromethyl)-1,2-thiazole-4-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC5BrF3N2S
Molecular Weight257.03 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1993
Halogen ContentF/Br-containing
Nitrogen Atoms2
Sulfur Atoms1

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