2-Amino-N-methylbenzenesulfonamide CAS 16288-77-0
| CAS No. | 16288-77-0 |
| Molecular Formula | C7H10N2O2S |
| Molecular Weight | 186.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, 2-Amino-N-methylbenzenesulfonamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 186.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2-Amino-N-methylbenzenesulfonamide (CAS 16288-77-0) is a high-purity analytical reference standard with the molecular formula C7H10N2O2S and a molecular weight of 186.23 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H10N2O2S |
| Molecular Weight | 186.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 3-Amino-5-methylbenzenesulfonamide (CAS 1017448-52-0)
- 3-Amino-2-methylbenzenesulfonamide (CAS 1036585-24-6)
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Recommended Standards
- 2-(Ethylamino)-4-methyl-1,3-thiazole-5-carboxylic acid (CAS 162651-09-4)
- 2-(morpholin-4-yl)-4,5-dihydro-1,3-thiazol-4-one (CAS 16781-67-2)
- 2-(Dimethylamino)-4-methyl-1,3-thiazole-5-carboxylic acid (CAS 162650-62-6)
- Azetidin-3-yl(4-fluoropiperidin-1-yl)methanone (CAS 1681019-84-0)
- Haloperidol HCl (CAS 1511-16-6)
- 5-(2-Cyanophenyl)nicotinonitrile (CAS 1346691-52-8)
- 1-(2,6-Dichlorophenyl)-3-(3,4,5-trifluorophenyl)propan-1-one (CAS 898778-70-6)
- (S)-(5-Fluoro-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol (CAS 1420537-26-3)
- 1-[(3-Bromophenoxy)methyl]-1H-pyrazole-3-carboxylic acid (CAS 1006487-34-8)
- 2-(Fluoromethyl)benzene-1-sulfonyl chloride (CAS 1783925-97-2)
- 4-Amino-1-naphthalenesulfonic Acid (CAS 84-86-6)
- 2,5-Dibromo-3-(difluoromethyl)pyridin-4-ol (CAS 1806838-73-2)
- 3-(Chloromethyl)-1-phenyl-1h-pyrazole (CAS 83959-39-1)
- Exenatide Acetate (CAS 141732-76-5)
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