4-Bromo 17-beta-Estradiol CAS 1630-83-7
| CAS No. | 1630-83-7 |
| Molecular Formula | C18H23BrO2 |
| Molecular Weight | 351.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 351.28 g/mol gives 4-Bromo 17-beta-Estradiol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Bromo 17-beta-Estradiol (CAS 1630-83-7), molecular formula C18H23BrO2 and molecular weight 351.28 g/mol, is a CATO reference standard with documented purity and traceability.
4-Bromo 17-beta-Estradiol (C18H23BrO2) contains a steroid core, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Bromo 17-beta-Estradiol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H23BrO2 |
| Molecular Weight | 351.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Br-containing |
Related Bromo Standards
- 2-Bromo 17-beta-Estradiol (CAS 15833-07-5)
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- 1-[(5-Bromo-2-fluoro-4-methylsulfonyl)phenyl]-homopiperazine (CAS 1020722-22-8)
- Ethyl 6-bromo-4-(diethylamino)quinoline-3-carboxylate (CAS 1215814-78-0)
- 1-((4-Bromo-2-fluorophenyl)sulfonyl)-4-ethylpiperazine (CAS 1331185-87-5)
- 1-(4'-Bromo-[1,1'-biphenyl]-4-yl)-2-phenylethan-1-one (CAS 60312-95-0)
Recommended Standards
- (S)-2-Amino-3-(4-((diethoxyphosphoryl)difluoromethyl)phenyl)propanoic acid (CAS 160751-42-8)
- [4-(Hydroxymethyl)-1-[4-phenyl-6-(trifluoromethyl)pyrimidin-2-yl]-1H-1,2,3-triazol-5-yl]methanol (CAS 861210-55-1)
- 1,1-Dimethyl-3-(5-oxo-2-(trifluoromethyl)-5H-chromeno[2,3-b]pyridin-3-yl)urea (CAS 303995-23-5)
- (1-Ethyl-5-hydroxy-1H-pyrazol-4-yl)-(4-oxazol-2-yl-2-trifluoromethyl-phenyl)-methanone (CAS 1231641-39-6)
- 1-Cyclopropyl-3-(5-methylthiophen-2-yl)propane-1,3-dione (CAS 1340519-57-4)
- 2-Propenoic acid, 2-methyl-, dodecyl ester, polymer with 4-ethenylpyridine and tetradecyl 2-methyl-2-propenoate (CAS 125594-58-3)
- 2-Bromo-6-chloro-4-nitroaniline (CAS 99-29-6)
- (2E)-2-{[(4-hydroxy-2-methylphenyl)amino]methylidene}-4,4-dimethyl-3-oxopentanenitrile (CAS 1025306-51-7)
- 6,7-Baccatin III (CAS 158830-50-3)
- 2-[cyclopentyl(methyl)amino]-2-methylpropanoic acid hydrochloride (CAS 1423034-86-9)
- 2-(4-Chlorophenyl)-8-ethylquinoline-4-carboxylic acid (CAS 590350-43-9)
- 3-[2-(Benzyloxy)phenyl]propanoic acid (CAS 48179-00-6)
- Perindopril Impurity 27 (CAS CATO-C4X-125227)
- Semaglutide impurity 194 (CAS CATO-C4X-2226194)
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