5-[3-Bromo-5-(trifluoromethyl)phenyl]-oxazole CAS 1630747-25-9
| CAS No. | 1630747-25-9 |
| Molecular Formula | C10H5BrF3NO |
| Molecular Weight | 292.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-[3-Bromo-5-(trifluoromethyl)phenyl]-oxazole (CAS 1630747-25-9) is a high-purity analytical reference standard with the molecular formula C10H5BrF3NO and a molecular weight of 292.05 g/mol.
The molecular framework of 5-[3-Bromo-5-(trifluoromethyl)phenyl]-oxazole (C10H5BrF3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-[3-Bromo-5-(trifluoromethyl)phenyl]-oxazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H5BrF3NO |
| Molecular Weight | 292.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
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- 65735-07-1 3-Methyl-1,2-oxazole-5-carbonitrile DTXSID80611835 (CAS 65735-07-1)
- (3',4'-Dimethoxy-[1,1'-biphenyl]-4-yl)methanol (CAS 760987-73-3)
- (R)-3-(1-Aminoprop-2-yn-1-yl)-2-fluorobenzonitrile hydrochloride (CAS 2846110-09-4)
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