1-(4-Chlorophenyl)-2,5-dihydro-1H-pyrrole-2,5-dione CAS 1631-29-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1631-29-4
Molecular FormulaC10H6ClNO2
Molecular Weight207.61 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(4-Chlorophenyl)-2,5-dihydro-1H-pyrrole-2,5-dione CAS 1631-29-4 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-Chlorophenyl)-2,5-dihydro-1H-pyrrole-2,5-dione.

1-(4-Chlorophenyl)-2,5-dihydro-1H-pyrrole-2,5-dione (CAS 1631-29-4), molecular formula C10H6ClNO2 and molecular weight 207.61 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1-(4-Chlorophenyl)-2,5-dihydro-1H-pyrrole-2,5-dione (C10H6ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(4-Chlorophenyl)-2,5-dihydro-1H-pyrrole-2,5-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H6ClNO2
Molecular Weight207.61 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentCl-containing
Nitrogen Atoms1

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