2-(5-(4-Fluorophenyl)-1H-indol-3-yl)acetonitrile CAS 163105-49-5
| CAS No. | 163105-49-5 |
| Molecular Formula | C16H11FN2 |
| Molecular Weight | 250.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(5-(4-Fluorophenyl)-1H-indol-3-yl)acetonitrile (CAS 163105-49-5), molecular formula C16H11FN2 and molecular weight 250.27 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(5-(4-Fluorophenyl)-1H-indol-3-yl)acetonitrile (C16H11FN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 2-(5-(4-Fluorophenyl)-1H-indol-3-yl)acetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H11FN2 |
| Molecular Weight | 250.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorophenyl Standards
- 3-(3-Fluorophenyl)-1-oxa-3,8-diazaspiro[4.5]Decan-2-one (CAS 1047655-91-3)
- 3-(4-Fluorophenyl)-1-oxa-3,8-diazaspiro[4.5]Decan-2-one (CAS 1047655-95-7)
- 2-(4-(2-Fluorophenyl)-1H-indol-3-yl)acetonitrile (CAS 1214333-05-7)
- 2-(4-(4-Fluorophenyl)-1H-indol-3-yl)acetonitrile (CAS 1214338-52-9)
- 2-(5-(2-Fluorophenyl)-1H-indol-3-yl)acetonitrile (CAS 1214342-63-8)
- 2-(5-(3-Fluorophenyl)-1H-indol-3-yl)acetonitrile (CAS 1214342-74-1)
- 2-(6-(4-Fluorophenyl)-1H-indol-3-yl)acetonitrile (CAS 1214377-94-2)
- 2-(6-(3-Fluorophenyl)-1H-indol-3-yl)acetonitrile (CAS 1214383-76-2)
Recommended Standards
- 4-Hydroxy biphenyl sulfate sodium salt (CAS 16063-85-7)
- 2-((2-Methoxyphenyl)amino)thiazole-4-carboxylic acid (CAS 165682-74-6)
- cis-2-(4-Fluorobenzoyl)cyclohexane-1-carboxylic acid (CAS 154810-33-0)
- 2-[(4-methoxyphenyl)amino]-1,3-thiazole-4-carboxylic acid (CAS 165682-75-7)
- 3-Methyl-4-(trifluoromethoxy)picolinimidamide hydrochloride (CAS 1179360-01-0)
- (2R,4AR,6R,7S,8S,8aS)-6-methoxy-2-phenylhexahydropyrano[3,2-d][1,3]dioxine-7,8-diol (CAS 146863-04-9)
- 4-Ethoxybenzo[d]oxazole-2-carbonitrile (CAS 1806339-51-4)
- [2-(4-methyl-1,3-thiazol-2-yl)ethyl]urea (CAS 1334147-02-2)
- 4-((4-Bromo-1h-pyrazol-1-yl)methyl)benzonitrile (CAS 1006538-45-9)
- 2H-1,4-Benzoxazine-2,3(4H)-dione (CAS 3597-63-5)
- 1,2,4-Oxadiazolidine-3,5-dione (CAS 24603-68-7)
- 4-Benzyl 3-(tert-butyl) (S)-1,2,3-oxathiazolidine-3,4-dicarboxylate 2,2-dioxide (CAS 889459-00-1)
- 3-Ethoxy-4-((4-fluorobenzyl)oxy)benzoic acid (CAS 861452-90-6)
- Peptide Impurity 06 (CAS CATO-CPTD788806)
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