Tenapanor impurity 1 CAS 1631730-06-7
| CAS No. | 1631730-06-7 |
| Molecular Formula | C50H66Cl4N8O10S2 |
| Molecular Weight | 1145.05 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Tenapanor impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Tenapanor impurity 1 (CAS 1631730-06-7), a pharmacopoeial impurity reference standard (molecular formula C50H66Cl4N8O10S2, MW 1145.05 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Tenapanor impurity 1 (C50H66Cl4N8O10S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C50H66Cl4N8O10S2 |
| Molecular Weight | 1145.05 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 8 |
| Sulfur Atoms | 2 |
Related Tenapanor Standards
Recommended Standards
- Sialylfucosyllacto-N-tetraose (CAS 84061-53-0)
- Sialyl Lewis X-Lactose (CAS 127923-85-7)
- Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH (CAS 189696-01-3)
- N-Acetylneuraminyl-fucosyllacto-N-neo-tetraose from human milk (CAS 111216-36-5)
- Racecadotril Impurity 29 (CAS CATO-C4X-110629)
- Roxatidine Impurity 66 (CAS 2765350-63-6)
- Saxagliptin Impurity 29 (CAS 1496712-39-0)
- H-L-HYp-pna hcl (CAS 213271-05-7)
- 2-Amino-7H-pyrrolo[2,3-d]pyrimidin-4-ol (CAS 41687-92-7)
- tert-Butyl 3-hydroxy-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate (CAS 625098-86-4)
- 1-(2,4-Dimethyl-5-thiazolyl)-2-hydroxyethanone (CAS 122229-24-7)
- 3-(4-Chlorophenyl)imidazo[1,5-a]pyridine-1-carbaldehyde (CAS 446269-62-1)
- Boceprevir (CAS 394730-60-0)
- Semaglutide Impurity 176 (CAS CATO-C4X-2226176)
Why CATO?
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