Medroxyprogesterone Impurity N1 CAS 16319-93-0
| CAS No. | 16319-93-0 |
| Molecular Formula | C25H36O4 |
| Molecular Weight | 400.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Medroxyprogesterone Impurity N1 (CAS 16319-93-0), a pharmacopoeial impurity reference standard (molecular formula C25H36O4, MW 400.55 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Medroxyprogesterone Impurity N1 (C25H36O4) contains a flavonoid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 400.55 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Medroxyprogesterone Impurity N1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H36O4 |
| Molecular Weight | 400.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
Related Medroxyprogesterone Standards
- Medroxyprogesterone Acetate EP Impurity A (CAS 984-47-4)
- Medroxyprogesterone impurity 8 (CAS 136803-81-1)
- Medroxyprogesterone Acetate Impurity 7 (CAS 28018-91-9)
- Medroxyprogesterone Acetate Impurity 19 (CAS 71315-38-3)
- Medroxyprogesterone Acetate EP Impurity F (CAS 69688-15-9)
- Medroxyprogesterone Acetate EP Impurity D (CAS 2242-65-1)
- Medroxyprogesterone Acetate (CAS 71-58-9)
- Medroxyprogesterone Impurity 19 (CAS CATO-C4X-145719)
Recommended Standards
- Tert-butyl 4-(2-oxo-3,3-dipropylindolin-1-yl)piperidine-1-carboxylate (CAS 1358667-49-8)
- 4-(7-Amino-5,5-dimethyl-3-(methylimino)-3,5-dihydrodibenzo[b,e]silin-10-yl)-3-methylbenzoic acid (CAS 1807857-60-8)
- (7a)-7-Hydroxy-3-oxo-chola-1,4-dien-24-oic Acid Methyl Ester (CAS 125626-78-0)
- (1R,2R,3R)-2-(2,6-Dimethoxy-4-pentylphenyl)-6-methylene-3-(1-methylethenyl)cyclohexanol 1-Acetate (CAS 306734-01-0)
- Biotin impurity 18 (CAS 4375-00-2)
- Baclofen Impurity 37 (CAS CATO-C4X-101237)
- Mirabegron impurity 101 (CAS CATO-C4X-1032101)
- (R)-4-methylheptanoic acid (CAS 115109-01-8)
- 1-(9z-octadecenyl)-2-hydroxy-sn-glycero-3-phosphate ammonium salt 799279-68-8 (CAS 799279-68-8)
- [{2-[(4-Methylpiperazin-1-yl)amino]-2-oxoethyl}(phenyl)amino]acetic acid (CAS 1142204-93-0)
- 8-Bromo-6-chloro-2,2-dimethylchroman-4-one (CAS 1342530-69-1)
- Ethyl 6-Bromoimidazo[1,2-a]pyridine-2-carboxylate (CAS 67625-37-0)
- 2-Fluoro-6-(2-methoxyethoxy)aniline (CAS 131055-86-2)
- Semaglutide impurity 198 (CAS CATO-C4X-2226198)
Why CATO?
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