2-Chloro-3,5-dinitro-6-(trifluoromethyl)pyridine CAS 163238-99-1
| CAS No. | 163238-99-1 |
| Molecular Formula | C6HClF3N3O4 |
| Molecular Weight | 271.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 271.54 g/mol gives 2-Chloro-3,5-dinitro-6-(trifluoromethyl)pyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Chloro-3,5-dinitro-6-(trifluoromethyl)pyridine (CAS 163238-99-1) is a high-purity analytical reference standard with the molecular formula C6HClF3N3O4 and a molecular weight of 271.54 g/mol.
The molecular framework of 2-Chloro-3,5-dinitro-6-(trifluoromethyl)pyridine (C6HClF3N3O4) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6HClF3N3O4 |
| Molecular Weight | 271.54 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
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- 5,6-Dihydro-4H-1,3-thiazin-2-amine (CAS 30480-64-9)
- 1,4-Benzoquinone (CAS 106-51-4)
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- (3-Methoxy-4-(pyridin-4-ylmethoxy)phenyl)methanamine (CAS 954571-22-3)
- (R)-2-((tert-Butoxycarbonyl)amino)-3-(3,4-dichlorophenyl)propanoic acid (CAS 114873-13-1)
- Galanin-Like Peptide (porcine) trifluoroacetate salt (CAS 245114-96-9)
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