4,4,6-Trimethyl-1-phenyl-1,4-dihydropyrimidine-2-thiol CAS 16325-43-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4,4,6-Trimethyl-1-phenyl-1,4-dihydropyrimidine-2-thiol.

CATO supplies 4,4,6-Trimethyl-1-phenyl-1,4-dihydropyrimidine-2-thiol (CAS 16325-43-2), a certified reference material (molecular formula C13H16N2S, MW 232.34 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, 4,4,6-Trimethyl-1-phenyl-1,4-dihydropyrimidine-2-thiol is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 232.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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