Fmoc-Met(O?)-OH CAS 163437-14-7
| CAS No. | 163437-14-7 |
| Molecular Formula | C20H21NO6S |
| Molecular Weight | 403.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 403.45 g/mol gives Fmoc-Met(O?)-OH distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Fmoc-Met(O?)-OH (CAS 163437-14-7) is a high-purity analytical reference standard with the molecular formula C20H21NO6S and a molecular weight of 403.45 g/mol.
The molecular framework of Fmoc-Met(O?)-OH (C20H21NO6S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H21NO6S |
| Molecular Weight | 403.45 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Fmoc Standards
- N-Fmoc-3-hydroxy-D-phenylalanine (CAS 1217724-28-1)
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Recommended Standards
- Boc-Met-Gly-OSu (CAS 23446-04-0)
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- Gliquidone Impurity 7 (CAS CATO-C4X-30007)
- Tert-butyl (2R,4R)-4-hydroxy-2-(3-((4,4,4-trifluorobutyl)sulfonyl)propyl)pyrrolidine-1-carboxylate (CAS 1670273-20-7)
- 1-Acetyl-3-bromo-6-fluoroindole (CAS 1375064-49-5)
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- 4-(4-Nitrophenoxy)benzenesulfonyl chloride (CAS 61404-92-0)
- N-((3-Benzamidophenyl)carbamothioyl)-3,4,5-trimethoxybenzamide (CAS 330829-30-6)
- 7-Bromo-5-methyl-4-oxo-4,5-dihydrofuro[3,2-c]pyridine-2-carboxylic acid (CAS 2733461-26-0)
- 9,9-Bis(4-methoxyphenyl)-9H-fluorene (CAS 117766-40-2)
- Opicapone Impurity 6 (CAS CATO-C4X-24046)
- 2-Fluoro-1-methoxy-4-methoxymethoxybenzene (CAS 133788-99-5)
- Methyl 2-ethyl-6-methoxypyrimidine-4-carboxylate (CAS 1302581-50-5)
- Atrial Natriuretic Polypeptide (4-28), human (CAS 95896-08-5)
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