Benzyl (3R,4R)-3,4-dihydroxypyrrolidine-1-carboxylate CAS 163439-83-6
| CAS No. | 163439-83-6 |
| Molecular Formula | C12H15NO4 |
| Molecular Weight | 237.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Benzyl (3R,4R)-3,4-dihydroxypyrrolidine-1-carboxylate (CAS 163439-83-6), molecular formula C12H15NO4 and molecular weight 237.25 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Benzyl (3R,4R)-3,4-dihydroxypyrrolidine-1-carboxylate (C12H15NO4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Benzyl (3R,4R)-3,4-dihydroxypyrrolidine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H15NO4 |
| Molecular Weight | 237.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Nitrogen Atoms | 1 |
Recommended Standards
- 3,4-Dimethylbenzo[g]quinoline-5,10-dione (CAS 161237-39-4)
- 5-tert-Butyl 2-methyl pyridine-2,5-dicarboxylate (CAS 163587-55-1)
- (R)-1-(2-Methylfuran-3-carbonyl)piperidine-2-carboxylic acid (CAS 1569988-42-6)
- Methyl 8-methoxy-6-oxo-2,3,4,6-tetrahydro-1H-quinolizine-9-carboxylate (CAS 1638612-50-6)
- 2-(3,4-Dimethoxyphenyl)imidazole (CAS 1119531-20-2)
- 1,3,6,7,8-Pentabromodibenzo[b,d]furan (CAS 617708-15-3)
- 2,2-Difluoro-3-methyl-but-3-enoic acid ethyl ester (CAS 1936641-34-7)
- 4-(1H-1,2,4-Triazol-3-yl)benzaldehyde (CAS 1022158-17-3)
- 6-Chloro-5-methyl-N-(quinolin-5-yl)indoline-1-carboxamide (CAS 162100-15-4)
- 4-(4-(Aminomethyl)-3-methoxyphenoxy)butanoic acid (CAS 213120-60-6)
- 4-(4-Fluorobenzamido)benzoic acid (CAS 54057-46-4)
- Mirogabalin Impurity 81 (CAS 1138246-18-0)
- (5-((Tert-butoxycarbonyl)amino)thiophen-3-yl)boronic acid (CAS 889451-13-2)
- Gastric Inhibitory Polypeptide (3-42) (human) trifluoroacetate salt (CAS 1802086-25-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com