4-(2-Chlorobenzylidene)-2-(p-tolyl)oxazol-5(4H)-one CAS 16352-74-2
| CAS No. | 16352-74-2 |
| Molecular Formula | C17H12ClNO2 |
| Molecular Weight | 297.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-(2-Chlorobenzylidene)-2-(p-tolyl)oxazol-5(4H)-one (CAS 16352-74-2), a certified reference material (molecular formula C17H12ClNO2, MW 297.74 g/mol) for analytical method development and quality control.
The molecular framework of 4-(2-Chlorobenzylidene)-2-(p-tolyl)oxazol-5(4H)-one (C17H12ClNO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(2-Chlorobenzylidene)-2-(p-tolyl)oxazol-5(4H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H12ClNO2 |
| Molecular Weight | 297.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorobenzylidene Standards
- 2-Benzyl-4-(4-chlorobenzylidene)oxazol-5(4H)-one (CAS 121487-23-8)
- 3-((4-Chlorobenzylidene)amino)-2-methylquinazolin-4(3H)-one (CAS 1769-12-6)
- 4-(4-Chlorobenzylidene)-2-(p-tolyl)oxazol-5(4H)-one (CAS 90124-87-1)
- 3-(2-(4-Chlorobenzylidene)hydrazinyl)quinoxalin-2(1H)-one (CAS 129227-26-5)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com