N-Acetyl-L-serine CAS 16354-58-8
| CAS No. | 16354-58-8 |
| Molecular Formula | C5H9NO4 |
| Molecular Weight | 147.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-Acetyl-L-serine.
N-Acetyl-L-serine (CAS 16354-58-8), molecular formula C5H9NO4 and molecular weight 147.13 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-Acetyl-L-serine (C5H9NO4) is characterized by a carbohydrate-derived structure, an amide group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-Acetyl-L-serine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H9NO4 |
| Molecular Weight | 147.13 g/mol |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 1 |
Recommended Standards
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- 3-(aminomethyl)-4,4-dimethylpentanoic acid hydrochloride (CAS 1461713-77-8)
- N-(3-(2-Oxopyrrolidin-1-yl)phenyl)furan-2-carboxamide (CAS 940777-63-9)
- 2-((3S,4R)-3-Hydroxy-2,2-dimethyl-6-(trifluoromethoxy)chroman-4-yl)isoindolin-1-one (CAS 124916-54-7)
- Droperidol EP Impurity B HCl (CAS 1026015-45-1 (free base))
- (1R,2R)-N1,N2-Dibenzylcyclohexane-1,2-diamine (CAS 143443-23-6)
- tert-Butyl 4-((5-nitropyridin-2-yl)thio)piperidine-1-carboxylate (CAS 1353981-45-9)
- Semaglutide Impurity 131 (CAS 2618647-80-4)
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