6-Amino-1-(4-fluorophenyl)pyrimidine-2,4(1H,3H)-dione CAS 16357-51-0
| CAS No. | 16357-51-0 |
| Molecular Formula | C10H8FN3O2 |
| Molecular Weight | 221.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Amino-1-(4-fluorophenyl)pyrimidine-2,4(1H,3H)-dione.
CATO supplies 6-Amino-1-(4-fluorophenyl)pyrimidine-2,4(1H,3H)-dione (CAS 16357-51-0), a certified reference material (molecular formula C10H8FN3O2, MW 221.19 g/mol) for analytical method development and quality control.
6-Amino-1-(4-fluorophenyl)pyrimidine-2,4(1H,3H)-dione (C10H8FN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-Amino-1-(4-fluorophenyl)pyrimidine-2,4(1H,3H)-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8FN3O2 |
| Molecular Weight | 221.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 5-Amino-3-(2-fluorophenyl)-1,2-oxazole-4-carboxamide (CAS 1005509-34-1)
- 5-Amino-1-(3-fluorophenyl)-1H-pyrazole-4-carboxylic acid (CAS 1034142-09-0)
- 5-Amino-1-(3-fluorophenyl)-1H-1,2,3-triazole-4-carboxamide (CAS 1105195-29-6)
- 1-(2-Amino-4-fluorophenyl)-1h-pyrazole-3-carboxylic acid (CAS 1170797-99-5)
- 5-Amino-2-(3-fluorophenyl)oxazole-4-carboxamide (CAS 1217863-04-1)
- 1-(4-Amino-2-fluorophenyl)-1h-pyrazole-3-carboxylic acid (CAS 1356543-24-2)
- Methyl 2-amino-5-fluoroquinazoline-7-carboxylate (CAS 1422188-61-1)
- 6-Amino-1-(3-fluorophenyl)pyrimidine-2,4(1H,3H)-dione (CAS 18464-28-3)
Recommended Standards
- 1-(3-fluoro-5-methylphenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1511171-91-7)
- 1-(3-Fluoro-4-methoxyphenyl)-1H-1,2,3-triazole-4-carbaldehyde (CAS 1481567-35-4)
- 6-Amino-1-(2-fluorophenyl)pyrimidine-2,4(1H,3H)-dione (CAS 18507-17-0)
- 5-Amino-1-(4-fluorophenyl)pyrazole-4-carboxylic Acid (CAS 187949-90-2)
- 4-Ethoxy-2,3-dimethylbenzene-1-sulfonyl chloride (CAS 1094296-27-1)
- 2-Fluoro-N-methyl-3-(trifluoromethyl)aniline (CAS 1261808-48-3)
- Methyl 4-(Aminomethyl)pyridine-2-carboxylate Dihydrochloride (CAS 1072438-55-1)
- 7-bromo-3-iodoimidazo[1,2-a]pyridine (CAS 1246184-55-3)
- tert-Butyl 4-(2-hydroxyphenyl)-5,6-dihydropyridine-1(2H)-carboxylate (CAS 1269025-34-4)
- Tenofovir disoproxil Impurity 119 (CAS CATO-C4X-1076119)
- N-(4-(5-(furan-2-yl)-1,3,4-oxadiazol-2-yl)phenyl)-2-phenylacetamide (CAS 351521-31-8)
- 2-Bromo-6-(difluoromethyl)-5-fluoronicotinonitrile (CAS 1805009-43-1)
- 2-Demethyl Colchicine 2-O-Sulfate (CAS 1391052-56-4)
- Liraglutide (13-21) TFA Salt (CAS CATO-C4X-19928)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com