4-Chloropyrimidine-5-carbonitrile CAS 16357-68-9
| CAS No. | 16357-68-9 |
| Molecular Formula | C5H2ClN3 |
| Molecular Weight | 139.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-Chloropyrimidine-5-carbonitrile (CAS 16357-68-9) is a high-purity analytical reference standard with the molecular formula C5H2ClN3 and a molecular weight of 139.54 g/mol.
4-Chloropyrimidine-5-carbonitrile (C5H2ClN3) contains a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H2ClN3 |
| Molecular Weight | 139.54 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloropyrimidine Standards
- 5-Chloropyrimidine-4-carbonitrile (CAS 114969-65-2)
- 2-Chloropyrimidine-4-carbonitrile (CAS 75833-38-4)
- 5-Chloropyrimidine-2-carbonitrile (CAS 38275-56-8)
- 6-Chloropyrimidine-4-carbonitrile (CAS 939986-65-9)
- 2-Chloropyrimidine-4-carbaldehyde (CAS 944901-22-8)
- 4-Chloropyrimidine-5-carbaldehyde (CAS 933703-03-8)
- 5-Chloropyrimidine-2-carbaldehyde (CAS 944900-20-3)
- 2-Chloropyrimidine-4,5-diamine (CAS 14631-08-4)
Recommended Standards
- 3-Chloropyridazine-4-carbonitrile (CAS 1445-56-3)
- 2-chloro-5-Pyrimidinecarbonitrile (CAS 1753-50-0)
- 6-Chloropyridazine-4-carbonitrile (CAS 1780924-86-8)
- Barium hydride (CAS 13477-09-3)
- 4-(6-Methoxy-2H-chromen-3-yl)-2-methyl-5-oxo-5H-indeno[1,2-b]pyridine-3-carbonitrile (CAS 866145-00-8)
- (1-((4-Bromophenyl)sulfonyl)piperidin-4-yl)methanol (CAS 937012-94-7)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrrole-2-carbaldehyde (CAS 321430-69-7)
- 3-(1H,1H,9H-Perfluorononyloxy)-1,2-propenoxide (CAS 125370-60-7)
- 3-((4-Aminophenyl)amino)cyclohex-2-en-1-one (CAS 400873-20-3)
- 2-Ethyl-N-(piperidin-3-yl)hexanamide hydrochloride (CAS 1832607-14-3)
- 1-Chloro-2-methoxy-5-nitro-3-(propan-2-yloxy)benzene (CAS 1394984-34-9)
- N-Boc-α-methyl-D,L-leucine (CAS 97534-52-6)
- (4R)-4-(3,4,5-Trifluorophenyl)pyrrolidin-2-one (CAS 1651179-16-6)
- Experimental Allergic Encephalitogenic Peptide (CAS 29705-92-8)
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