2-Ethyl-5-fluoro-1H-indole CAS 163688-20-8
| CAS No. | 163688-20-8 |
| Molecular Formula | C10H10FN |
| Molecular Weight | 163.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Ethyl-5-fluoro-1H-indole.
2-Ethyl-5-fluoro-1H-indole (CAS 163688-20-8), molecular formula C10H10FN and molecular weight 163.19 g/mol, is a CATO reference standard with documented purity and traceability.
2-Ethyl-5-fluoro-1H-indole (C10H10FN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10FN |
| Molecular Weight | 163.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 2-(4-Fluoro-3,5-dimethylphenyl)acetonitrile (CAS 1000513-61-0)
- 4-Fluoro-5,7-dimethyl-1H-indole (CAS 1190320-77-4)
- 3-Ethyl-7-fluoro-1h-indole (CAS 1360902-63-1)
- 3-Ethyl-6-fluoro-1h-indole (CAS 1360940-05-1)
- 3-Ethyl-5-fluoro-1h-indole (CAS 1360962-77-1)
- 3-Ethyl-4-fluoro-1H-indole (CAS 1360962-90-8)
- 2-Fluoro-4-isopropylbenzonitrile (CAS 1369834-93-4)
- 6-Ethyl-5-fluoro-1H-indole (CAS 1510828-27-9)
Recommended Standards
- 4-(4-Fluorophenyl)but-3-yn-2-amine (CAS 1602914-48-6)
- 5-(3-Fluorophenyl)-3,4-dihydro-2H-pyrrole (CAS 164737-45-5)
- Thiomorpholine-3-carboxylic acid 1-oxide (CAS 156474-26-9)
- Tetrahydro-1,4-thiazepan-5-one-1,1-dioxide (CAS 16906-20-0)
- Ethyl 2-(2-chloro-5-fluorophenyl)imidazo[1,2-a]pyridine-3-carboxylate (CAS 1923068-94-3)
- Diisobutylaluminum Chloride (CAS 1779-25-5)
- 5-(Benzenesulfonyl)-4-(2-chlorophenyl)-2-phenylpyrimidine (CAS 339107-55-0)
- 4-(4-Bromophenyl)-2,2-dimethylbutanoic acid (CAS 1267365-75-2)
- 4-(4-Chlorophenyl)-2-[(E)-2-[(4-methoxyphenyl)amino]ethenyl]-6-methylpyridine-3,5-dicarbonitrile (CAS 337924-13-7)
- (4-Methoxybenzyl)(4-nitrobenzyl)amine hydrobromide (CAS 1609395-90-5)
- 5-Phenylpentanoyl chloride (CAS 20371-41-9)
- (3AR,9bs)-4-phenyl-3a,4,5,9b-tetrahydro-3h-cyclopenta[c]quinoline-6-carboxylic acid (CAS 1415814-68-4)
- Ethyl 2-(pyridin-3-yl)thiazole-4-carboxylate (CAS 39067-28-2)
- Semaglutide impurity 91 (CAS CATO-C4X-222691)
Why CATO?
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