Ethyl 6,6,6-Trifluoro-3-oxohexanoate CAS 163714-65-6
| CAS No. | 163714-65-6 |
| Molecular Formula | C8H11F3O3 |
| Molecular Weight | 212.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Ethyl 6,6,6-Trifluoro-3-oxohexanoate (CAS 163714-65-6), molecular formula C8H11F3O3 and molecular weight 212.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 6,6,6-Trifluoro-3-oxohexanoate (C8H11F3O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Ethyl 6,6,6-Trifluoro-3-oxohexanoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H11F3O3 |
| Molecular Weight | 212.17 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
Related Ethyl Standards
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Recommended Standards
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- 3-Ethyl-N-phenyl-[1,2,4]triazolo-[4,3-a]pyridine-8-sulfonamide (CAS 1291487-06-3)
- Ethyl 2-(2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)acetate hydrochloride (CAS 77276-91-6)
- 2-(2-Chloropyridin-3-yl)-1-(3-fluorobenzyl)-5,6-dimethyl-1H-benzo[d]imidazole (CAS 860787-69-5)
- 4-((1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)oxy)phthalonitrile (CAS 906673-33-4)
- 1-[4-(Trifluoromethyl)phenyl]ethane-1,2-diamine (CAS 69810-83-9)
- Edoxaban Impurity 60 (p-Toluenesulfonic acid) (CAS CATO-C4X-106360)
- 6-[(tert-Butyldimethylsilyloxy)methyl]picolinaldehyde (CAS 162084-83-5)
- Semaglutide Impurity 189 (CAS CATO-C4X-2226189)
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