Ethyl 5-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole-3-carboxylate CAS 163720-43-2
| CAS No. | 163720-43-2 |
| Molecular Formula | C12H9F3N2O3 |
| Molecular Weight | 286.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ethyl 5-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Ethyl 5-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole-3-carboxylate (CAS 163720-43-2) is a high-purity analytical reference standard with the molecular formula C12H9F3N2O3 and a molecular weight of 286.21 g/mol.
Ethyl 5-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole-3-carboxylate (C12H9F3N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H9F3N2O3 |
| Molecular Weight | 286.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
- 1-((3-(Trifluoromethyl)phenoxy)methyl)-1H-pyrazole-3-carboxylic acid (CAS 1004193-05-8)
- 3-(5-(4-(Trifluoromethyl)phenyl)-1,3,4-oxadiazol-2-yl)propanoic acid (CAS 1179161-29-5)
- Ethyl 5-(3-(trifluoromethyl)phenyl)-1,3,4-oxadiazole-2-carboxylate (CAS 1432053-94-5)
- Ethyl 5-(4-(trifluoromethyl)phenyl)-[1,2,4]oxadiazole-3-carboxylate (CAS 151098-18-9)
- Ethyl 3-(4-(trifluoromethyl)phenyl)-1,2,4-oxadiazole-5-carboxylate (CAS 163719-82-2)
- 2-{5-[3-(trifluoromethyl)phenyl]-2H-1,2,3,4-tetrazol-2-yl}acetohydrazide (CAS 729578-99-8)
- 3-(3-(3-(Trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)propanoic acid (CAS 866018-88-4)
- 3-(5-(3-(Trifluoromethyl)phenyl)-1,3,4-oxadiazol-2-yl)propanoic acid (CAS 923825-48-3)
Recommended Standards
- 2-(2-fluoro-5-nitrophenyl)-1,3-isoindolinedione (CAS 166658-69-1)
- 1-(1,1,2,3,3,3-Hexafluoro-propoxy)-2-isopropyl-benzene (CAS 157554-82-0)
- 3-(3-Bromophenoxy)-N,N-diethylpropan-1-amine (CAS 1704065-25-7)
- Ethyl 4-hydroxy-7-(trifluoromethyl)-1,8-naphthyridine-3-carboxylate (CAS 151099-11-5)
- 2-Amino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic Acid Ethyl Ester (CAS 305834-79-1)
- 2-Chloro-4-(hydroxymethyl)-6-methoxypyridine (CAS 193001-91-1)
- tert-Butyl (1-(2-amino-1-(p-tolyl)ethyl)pyrrolidin-3-yl)carbamate (CAS 886365-29-3)
- N-((1-(2,2-Difluoroethyl)-5-methyl-1H-pyrazol-4-yl)methyl)-1-methyl-1H-pyrazol-4-amine hydrochloride (CAS 1855940-74-7)
- 2-((1H-Imidazol-4-yl)amino)ethanol (CAS 799814-23-6)
- 4-(Methanesulfonylmethyl)-5-methylthiophene-2-carboxylic acid (CAS 1394040-61-9)
- Benzyl 3-(4-hydroxyphenyl)propanoate (CAS 31770-76-0)
- 4-Chloro-2,6-difluorophenol (CAS 164790-68-5)
- S-(1,2-Diformylpyrazolidin-4-yl) ethanethioate (CAS 216854-55-6)
- Anorexigenic Peptide (CAS 69275-10-1)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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