(trans-4-(Difluoromethoxy)cyclohexyl)methanol CAS 1637310-79-2
| CAS No. | 1637310-79-2 |
| Molecular Formula | C8H14F2O2 |
| Molecular Weight | 180.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (trans-4-(Difluoromethoxy)cyclohexyl)methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(trans-4-(Difluoromethoxy)cyclohexyl)methanol (CAS 1637310-79-2) is a high-purity analytical reference standard with the molecular formula C8H14F2O2 and a molecular weight of 180.19 g/mol.
The molecular framework of (trans-4-(Difluoromethoxy)cyclohexyl)methanol (C8H14F2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H14F2O2 |
| Molecular Weight | 180.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
Related trans Standards
- (4-(Difluoromethoxy)cyclohexyl)methanol (CAS 1692262-99-9)
- (2-(Difluoromethoxy)cyclohexyl)methanol (CAS 2306278-06-6)
- 4-(Difluoromethoxy)-1,2-difluorobenzene (CAS 1226153-51-0)
- 1-(Difluoromethoxy)-2,4-difluoro-benzene (CAS 1226194-39-3)
- 1-(Difluoromethoxy)-3,5-difluorobenzene (CAS 1400899-01-5)
- 2-(Difluoromethoxy)-1,4-difluorobenzene (CAS 1404193-91-4)
- 1-(Difluoromethoxy)-2,3-difluorobenzene (CAS 1404194-70-2)
- 2-(Difluoromethoxy)-1,3-difluorobenzene (CAS 1404195-17-0)
Recommended Standards
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