4'-Chlorospiro[cyclopropane-1,3'-indolin]-2'-one CAS 1637752-36-3
| CAS No. | 1637752-36-3 |
| Molecular Formula | C10H8ClNO |
| Molecular Weight | 193.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4'-Chlorospiro[cyclopropane-1,3'-indolin]-2'-one (CAS 1637752-36-3), molecular formula C10H8ClNO and molecular weight 193.63 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 4'-Chlorospiro[cyclopropane-1,3'-indolin]-2'-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 193.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H8ClNO |
| Molecular Weight | 193.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorospiro Standards
- 6'-Chlorospiro[cyclopropane-1,1'-isoindolin]-3'-one (CAS 1396777-82-4)
- 7'-Chlorospiro[cyclopropane-1,3'-indolin]-2'-one (CAS 1403564-65-7)
- 6'-Chlorospiro[cyclopropane-1,3'-indolin]-2'-one (CAS 83419-49-2)
- 6'-Chlorospiro[cyclobutane-1,3'-indoline] (CAS 1403899-03-5)
- 6'-Chlorospiro[cyclopropane-1,3'-pyrrolo[3,2-c]pyridin]-2'(1'H)-one (CAS 1642801-92-0)
- 5-chlorospiro[1H-pyrrolo[3,2-b]pyridine-3,1'-cyclopropane]-2-one (CAS 2766107-43-9)
- 6-chlorospiro[1H-pyrrolo[3,2-b]pyridine-3,1'-cyclopropane]-2-one (CAS 2168639-48-1)
- 7-chlorospiro[1H-pyrrolo[2,3-c]pyridine-3,1'-cyclopropane]-2-one (CAS 2168099-56-5)
Recommended Standards
- 2-Chloro-5,6-dihydro-4H-imidazo[1,5,4-de]quinoxaline (CAS 163120-51-2)
- 7-Chloro-6-methoxyquinoline (CAS 1643877-89-7)
- 1-(2-Chloroallyl)-1H-benzo[d][1,2,3]triazole (CAS 162519-36-0)
- (7-chloroquinolin-2-yl)methanol (CAS 165111-36-4)
- 3-(Pyridin-3-yl)thiophene-2-carboxylic acid (CAS 1214326-28-9)
- 3-Acetoxy-2,6-dichlorobenzophenone (CAS 890100-30-8)
- 3-((ethyl(nitroso)amino)methyl)benzenesulfonic acid (CAS CATO-C3D-26215)
- (Z)-3-Bromo-3-phenylacrylaldehyde (CAS 14804-59-2)
- 5-Ethynylpyridazin-3(2H)-one (CAS 1933587-79-1)
- 2-(2-Aminoethoxy)isoindoline-1,3-dione (CAS 848980-29-0)
- 84633-28-3 Eurycomanol Picrasa-3,13(21)-dien-16-one, 11,20-epoxy-1,2,11,12,14,15-hexahydroxy-, (1beta,2alpha,11beta,12alpha,15beta)- (1beta,2alpha,11beta,12alpha,15beta)-11,20-Epoxy-1,2,11,12,14,15-hexahydroxypicrasa-3,13(21)-dien-16-one (CAS 84633-28-3)
- 4-Bromo-N-((5-((4-(tert-butyl)benzyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)methyl)benzenesulfonamide (CAS 338794-55-1)
- 3-Iodo-4-isobutoxybenzoic acid (CAS 1131614-19-1)
- Semaglutide Impurity 163 (x TFA Salt) (CAS CATO-C4X-2226163)
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