(1R,4S)-7-Bromo-2,3,4,5-tetrahydro-1,4-methano-1H-1,5-benzodiazepine CAS 1638604-47-3
| CAS No. | 1638604-47-3 |
| Molecular Formula | C10H11BrN2 |
| Molecular Weight | 239.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(1R,4S)-7-Bromo-2,3,4,5-tetrahydro-1,4-methano-1H-1,5-benzodiazepine (CAS 1638604-47-3), molecular formula C10H11BrN2 and molecular weight 239.11 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (1R,4S)-7-Bromo-2,3,4,5-tetrahydro-1,4-methano-1H-1,5-benzodiazepine (C10H11BrN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures (1R,4S)-7-Bromo-2,3,4,5-tetrahydro-1,4-methano-1H-1,5-benzodiazepine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H11BrN2 |
| Molecular Weight | 239.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 5-Bromospiro[chromane-2,1'-cyclopropane] (CAS 1637490-78-8)
- 6-Bromo-2,2-dimethyl-2,3-dihydro-1H-inden-1-one (CAS 165730-10-9)
- 6-Bromo-1-isopropyl-1H-pyrrolo[3,2-c]pyridine (CAS 1612172-57-2)
- 6-Bromo-2-isopropyl-2H-indazole (CAS 1683546-11-3)
- Ethyl (R)-2-((methylsulfonyl)oxy)propanoate (CAS 68331-44-2)
- S-methyl 2-methylbutanethioate (CAS 42075-45-6)
- 11-(5-Fluoropyrimidin-2-yl)-8-oxa-2,11-diazaspiro[5.6]dodecane (CAS 1422067-25-1)
- Butylpropylsulfamoyl chloride (CAS 1349716-26-2)
- tert-butyl 2-cyano-2-(5-nitropyridin-2-yl)acetate (CAS 914223-27-1)
- 2-(4-Methoxyphenoxy)butanoyl chloride (CAS 679837-25-3)
- Furan-2-ylmethyl 4'-hexyl-[1,1'-biphenyl]-4-carboxylate (CAS 920270-20-8)
- 4-(Aminomethyl)-1-ethyl-N,N-dimethylpiperidin-4-amine (CAS 891656-66-9)
- Ethyl 3-amino-5-(tert-butyl)thiophene-2-carboxylate (CAS 439693-51-3)
- Semaglutide impurity 93 (CAS CATO-C4X-222693)
Why CATO?
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