(3S)-3-(difluoromethoxy)piperidine;hydrochloride CAS 1638744-46-3
| CAS No. | 1638744-46-3 |
| Molecular Formula | C6H11F2NO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (3S)-3-(difluoromethoxy)piperidine;hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(3S)-3-(difluoromethoxy)piperidine;hydrochloride (CAS 1638744-46-3), molecular formula C6H11F2NOHCl and molecular weight 187.61 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (3S)-3-(difluoromethoxy)piperidine;hydrochloride (C6H11F2NOHCl) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H11F2NO HCl |
| Molecular Weight | 187.61 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 3-[(2-Chloro-phenylamino)-methyl]-7-methoxy-1H-quinolin-2-one (CAS 483291-05-0)
- Ethyl 7-methoxypyrazolo[1,5-a]pyridine-3-carboxylate (CAS 1352398-15-2)
- 1,3-Di(1H-tetrazol-5-yl)propane (CAS 26670-17-7)
- 3-Chloro-4-[2,6-dinitro-4-(trifluoromethyl)phenoxy]aniline (CAS 338412-96-7)
- Methyl 3-bromo-2-(trifluoromethyl)benzoate (CAS 1214323-47-3)
- n-(2-Iodophenyl)-3,5-dimethyl-1h-pyrazole-4-sulfonamide (CAS 1045862-10-9)
- 8-((2-(Dimethylamino)ethyl)amino)-5-(hydroxymethyl)-9-oxo-9H-xanthen-2-yl 4-methylbenzenesulfonate (CAS 86456-22-6)
- tert-Butyl (3R,4S)-3-fluoro-4-hydroxypyrrolidine-1-carboxylate (CAS 1174020-49-5)
- Ethyl 6-nitro-8-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylate (CAS 1363405-53-1)
- Des-Pro31-Tirzepatide (CAS CATO-CPTD788943)
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