(3R)-3-(difluoromethoxy)piperidine;hydrochloride CAS 1638744-82-7
| CAS No. | 1638744-82-7 |
| Molecular Formula | C6H11F2NO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(3R)-3-(difluoromethoxy)piperidine;hydrochloride (CAS 1638744-82-7) is a high-purity analytical reference standard with the molecular formula C6H11F2NOHCl and a molecular weight of 187.61 g/mol.
The molecular framework of (3R)-3-(difluoromethoxy)piperidine;hydrochloride (C6H11F2NOHCl) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (3R)-3-(difluoromethoxy)piperidine;hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H11F2NO HCl |
| Molecular Weight | 187.61 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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- (4-(Difluoromethoxy)-2-fluorophenyl)boronic acid (CAS 1004775-34-1)
- 4,6-Bis(difluoromethoxy)-2-(methylthio)pyrimidine (CAS 100478-25-9)
- 1-(3-(Difluoromethoxy)phenyl)-3-(1,5-dimethyl-1H-pyrazol-4-yl)prop-2-en-1-one (CAS 1005647-45-9)
- Methyl 6-(4-(difluoromethoxy)phenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carboxylate (CAS 1011396-51-2)
Recommended Standards
- 1-Isopropyl-1H-pyrrole (CAS 7057-97-8)
- N-(3-ethoxy-4-nitrophenyl)acetamide (CAS 871895-08-8)
- 4-Methyl-2-morpholinone (CAS 18424-96-9)
- 2-((2,2-Dicyanovinyl)amino)benzoic acid (CAS 811841-69-7)
- 3-(3-Aminopropyl)-5,5-dimethylimidazolidine-2,4-dione (CAS 66387-39-1)
- 3-Methyl-2,6-dinitrobenzoic acid (CAS 3478-09-9)
- (3S)-3-Amino-3-(3-fluoro-4-hydroxyphenyl)propanoic acid (CAS 1027335-64-3)
- Benzyl 2,4-dichloro-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylate (CAS 1990514-48-1)
- (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(2,6-difluorophenyl)acetic acid (CAS 2350001-71-5)
- Semaglutide Impurity 139 (CAS CATO-C4X-2226139)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com