2-(3,3-difluorocyclobutylidene)acetonitrile CAS 1638761-44-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1638761-44-0
Molecular FormulaC6H5F2N
Molecular Weight129.11 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(3,3-difluorocyclobutylidene)acetonitrile CAS 1638761-44-0 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(3,3-difluorocyclobutylidene)acetonitrile.

2-(3,3-difluorocyclobutylidene)acetonitrile (CAS 1638761-44-0) is a high-purity analytical reference standard with the molecular formula C6H5F2N and a molecular weight of 129.11 g/mol.

The molecular framework of 2-(3,3-difluorocyclobutylidene)acetonitrile (C6H5F2N) is characterized by a nitrile group, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-(3,3-difluorocyclobutylidene)acetonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC6H5F2N
Molecular Weight129.11 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1993
Halogen ContentF-containing
Nitrogen Atoms1

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