1-(Tert-butoxycarbonyl)-2-(trifluoromethyl)-1H-indole-6-carboxylic acid CAS 1638767-49-3
| CAS No. | 1638767-49-3 |
| Molecular Formula | C15H14F3NO4 |
| Molecular Weight | 329.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(Tert-butoxycarbonyl)-2-(trifluoromethyl)-1H-indole-6-carboxylic acid.
1-(Tert-butoxycarbonyl)-2-(trifluoromethyl)-1H-indole-6-carboxylic acid (CAS 1638767-49-3) is a high-purity analytical reference standard with the molecular formula C15H14F3NO4 and a molecular weight of 329.27 g/mol.
Structurally, 1-(Tert-butoxycarbonyl)-2-(trifluoromethyl)-1H-indole-6-carboxylic acid (C15H14F3NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 329.27 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(Tert-butoxycarbonyl)-2-(trifluoromethyl)-1H-indole-6-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H14F3NO4 |
| Molecular Weight | 329.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Tert Standards
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Recommended Standards
- methyl 2-oxo-4-(4,4,4-trifluoro-3-oxobutyl)-1,2,3,4-tetrahydroquinoline-8-carboxylate (CAS 1402694-33-0)
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- 5-Oxo-5-((4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzyl)amino)pentanoic acid (CAS 1391025-56-1)
- (4Z)-4-{[(2,4-dimethoxyphenyl)amino]methylidene}-1-methyl-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-one (CAS 320425-06-7)
- [1,1’-Binaphthalen]-4-ylboronic acid (CAS 363607-69-6)
- 6-Bromo-1H-indole-3-ethanamine Hydrochloride (CAS 108061-77-4)
- 3,5-Dimethyltetrahydrofuran-3-amine (CAS 2060006-06-4)
- (E)-N-{7-[(Z)-2-(4-chlorophenyl)ethenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-N'-methoxymethanimidamide (CAS 303145-97-3)
- Tert-butyl (3-methyl-2-oxobutyl)carbamate (CAS 388113-93-7)
- 2-Chloro-4-ethynylbenzaldehyde (CAS 1849215-25-3)
- 3-(2,6-Dimethylphenyl)-1h-pyrazol-5-amine (CAS 1040723-87-2)
- 2-(6-Methoxyquinolin-3-yl)ethan-1-amine (CAS 1421601-37-7)
- 2-(4-(Tert-butyl)phenoxy)ethan-1-ol (CAS 713-46-2)
- D-Ala28-Tirzepatide (CAS CATO-CPTD788906)
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