2-(6-Fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)ethan-1-amine CAS 1638771-25-1

Purity 97%+In StockPharmaceutical Standards
CAS No.1638771-25-1
Molecular FormulaC9H10FN3
Molecular Weight179.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(6-Fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)ethan-1-amine CAS 1638771-25-1 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(6-Fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)ethan-1-amine.

2-(6-Fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)ethan-1-amine (CAS 1638771-25-1), molecular formula C9H10FN3 and molecular weight 179.19 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 2-(6-Fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)ethan-1-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 179.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(6-Fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)ethan-1-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC9H10FN3
Molecular Weight179.19 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1993
Halogen ContentF-containing
Nitrogen Atoms3

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