5-(2,2-Difluoropropoxy)pyrazine-2-carboxylic acid CAS 1640975-43-4
| CAS No. | 1640975-43-4 |
| Molecular Formula | C8H8F2N2O3 |
| Molecular Weight | 218.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-(2,2-Difluoropropoxy)pyrazine-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-(2,2-Difluoropropoxy)pyrazine-2-carboxylic acid (CAS 1640975-43-4) is a high-purity analytical reference standard with the molecular formula C8H8F2N2O3 and a molecular weight of 218.16 g/mol.
5-(2,2-Difluoropropoxy)pyrazine-2-carboxylic acid (C8H8F2N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8F2N2O3 |
| Molecular Weight | 218.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoropropoxy Standards
- 4-(2,2-Difluoropropoxy)-2-fluorobenzaldehyde (CAS 1627691-86-4)
- 6-(2,2-Difluoropropoxy)nicotinic acid (CAS 1373864-51-7)
- 4-(2,2-Difluoropropoxy)-3-methylbenzoic acid (CAS 1476027-91-4)
- (4-(2,2-Difluoropropoxy)pyrimidin-5-yl)methanamine (CAS 1799579-59-1)
- 4-(2,2-Difluoropropoxy)pyrimidine-5-carbonitrile (CAS 1799579-58-0)
- 4-(2,2-Difluoropropoxy)phenol (CAS 1783512-02-6)
- 3-(2,2-Difluoropropoxy)cyclobutan-1-ol (CAS 2156142-56-0)
- 2-(4-(2,2-Difluoropropoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2246678-87-3)
Recommended Standards
- Dimethyl (4-fluorobenzyl)phosphonate (CAS 156745-59-4)
- 6-(2,2-Difluoroethoxy)-2-methylpyrimidine-4-carboxylic acid (CAS 1713477-02-1)
- 4,9-Dihydroxy-7H-furo[3,2-g]chromen-7-one (CAS 14348-23-3)
- 5,5,6,6,6-Pentafluoro-2,2-dimethylhexan-3-one (CAS 177264-69-6)
- 1050509-48-2 4-(Cyclopropylmethoxy)piperidine--hydrogen chloride (1/1) DTXSID70589357 (CAS 1050509-48-2)
- 2-Methyl-7-(3-nitrophenyl)pyrazolo[1,5-a]pyrimidine (CAS 832739-45-4)
- CAS 2375194-37-7 (CAS 2375194-37-7)
- 4-Amino-2-phenylbutanoic acid (CAS 13080-10-9)
- 3-[5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl]morpholine hydrochloride (CAS 1803604-03-6)
- 2,4-Difluoro-3-(1-methylethoxy)benzaldehyde (CAS 1370025-56-1)
- 4-Amino-2-methyl-6-(methylthio)pyrimidine-5-carbonitrile (CAS 135158-59-7)
- 1-(tert-Butyl) 6a-methyl hexahydropyrrolo[3,4-b]pyrrole-1,6a-dicarboxylate (CAS 1424939-97-8)
- 6-Chloro-4-pyrimidinyl 4-piperidinyl etherhydrochloride (CAS 1185314-18-4)
- Insulin Degludec Impurity 10 (CAS CATO-C4X-215710)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com