4,4'-(1,4-Phenylene)bis(pyridine-2,6-dicarboxylic acid) CAS 164173-99-3
| CAS No. | 164173-99-3 |
| Molecular Formula | C20H12N2O8 |
| Molecular Weight | 408.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 4,4'-(1,4-Phenylene)bis(pyridine-2,6-dicarboxylic acid) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies 4,4'-(1,4-Phenylene)bis(pyridine-2,6-dicarboxylic acid) (CAS 164173-99-3), a certified reference material (molecular formula C20H12N2O8, MW 408.32 g/mol) for analytical method development and quality control.
The molecular framework of 4,4'-(1,4-Phenylene)bis(pyridine-2,6-dicarboxylic acid) (C20H12N2O8) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C20H12N2O8 |
| Molecular Weight | 408.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Nitrogen Atoms | 2 |
Related Phenylene Standards
- 9,9-(1,4-Phenylene)bis-9H-Carbazole (CAS 19287-68-4)
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- 2,2'-(1,2-Phenylene)bis(N,N-dimethylbenzo[d]oxazol-6-amine) (CAS 920491-91-4)
- 2,2'-(1,3-Phenylene)bis(1H-benzo[d]imidazole-6-carboxylic acid) (CAS 70553-62-7)
- 4,4'-(5,5'-(1,4-Phenylene)bis(1,3,4-oxadiazole-5,2-diyl))dianiline (CAS 22915-83-9)
- 2,2'-(1,4-Phenylene)bis(quinoline-4-carboxylic acid) (CAS 314022-35-0)
- 1,1'-(1,4-Phenylene)bis(3-hexylthiourea) (CAS 77006-71-4)
- 1,3-Phenylene tetraethyl bis(phosphate) (CAS 109592-16-7)
Recommended Standards
- 5,5'-(Pyrimidine-2,5-diyl)diisophthalic acid (CAS 1601485-40-8)
- (E)-2-(Trifluoromethyl)-N'-((E)-3-(2,4,6-trifluorophenyl)allylidene)benzenesulfonohydrazide (CAS 2786662-96-0)
- Methyl 3,5-bis(diethoxyphosphoryl)benzoate (CAS 1192028-86-6)
- 2-((5-(4-Bromophenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-cyano-3-methylbutan-2-yl)acetamide (CAS 775311-24-5)
- (R)-2-Amino-3-(hexylthio)propanoic acid (CAS 23884-44-8)
- 2-(2-Fluorophenyl)acetamide (CAS 326-63-6)
- 3-((6-(Phenylamino)-[1,2,5]oxadiazolo[3,4-b]pyrazin-5-yl)amino)propan-1-ol (CAS 382152-03-6)
- 3-Hydroxypropanehydrazide (CAS 24535-11-3)
- Roxadustat Impurity 102 (CAS CATO-C4X-2213102)
- 4-(4-Bromobenzenesulfonamido)benzoic acid (CAS 126145-99-1)
- 3-Fluoro-5-(4-phenoxyphenyl)isonicotinonitrile (CAS 1266161-20-9)
- 3-methyl-2-oxo-1,2-dihydroquinoline-6-sulfonyl chloride (CAS 1181714-73-7)
- 1-(2-Amino-2-cyclopropylethyl)-3-ethylurea (CAS 1343161-16-9)
- D-Pro38-Tirzepatide (CAS CATO-CPTD788901)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com