Cloxacillin EP Impurity B CAS 1642559-64-5
| CAS No. | 1642559-64-5 |
| Molecular Formula | C18H20ClN3O4S |
| Molecular Weight | 409.89 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Cloxacillin EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Cloxacillin EP Impurity B (CAS 1642559-64-5), a pharmacopoeial impurity reference standard (molecular formula C18H20ClN3O4S, MW 409.89 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C18H20ClN3O4S, Cloxacillin EP Impurity B contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 409.89 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C18H20ClN3O4S |
| Molecular Weight | 409.89 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Cloxacillin Standards
- Cloxacillin Impurity 31 (CAS CATO-C4X-159731)
- Cloxacillin Impurity 32 (CAS CATO-C4X-159732)
- Cloxacillin Impurity 37 (CAS CATO-C4X-159737)
- Cloxacillin Thiol Carboxylate Benzathine Salt (CAS 5230-02-4)
- Cloxacillin Impurity 6 (CAS CATO-C4X-15976)
- Cloxacillin Impurity 42 (CAS CATO-C4X-232142)
- Cloxacillin Impurity 13 (CAS 5053-36-1)
- Cloxacillin EP Impurity A (CAS 1642629-96-6)
Recommended Standards
- Rivaroxaban Impurity 161 (CAS 482305-98-6)
- Rivaroxaban Ethylamino Analog (CAS 2484747-45-5)
- 3,8-Dibromo-6-(bromomethyl)-5-methoxyquinoline (CAS 1257833-20-7)
- Rivaroxaban Impurity 15 (CAS CATO-C4X-109015)
- Metronidazole Impurity 31 (CAS CATO-C4X-140531)
- Entacapone Impurity 60 (CAS CATO-C4X-162960)
- Betamethasone Impurity 78 (CAS CATO-C4X-143778)
- 4-Fluoro-N-(3-iodophenyl)benzamide (CAS 443730-67-4)
- Fcnirpic; Bis[2-(5-cyano-4,6-difluorophenyl)pyridinato-c2,n](picolinato)iridium(iii) (CAS 665005-28-7)
- 3-Bromo-4-(oxetan-3-yloxy)benzoic acid (CAS 1597846-88-2)
- Piroxicam Impurity 16 (CAS 1797884-12-8)
- 2'-Methoxy-5'-methyl-[1,1'-biphenyl]-3-ol (CAS 1175976-25-6)
- 3,4-Difluoro[1,1-biphenyl]-3-carbaldehyde (CAS 927801-78-3)
- Semaglutide impurity 198 (CAS CATO-C4X-2226198)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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